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chronic osteomyelitis

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chronic osteomyelitis
Clinical medicine Osteomyelitis with bone necrosis due to compromised vascular supply, which may persist for yrs Risk factors Recent trauma, DM, hemodialysis, IV drug abuse. See Osteomyleitis.


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In chronic osteomyelitis, especially in adults after fractures, there may be recurring discharge from the region of the damaged bone.
Tobramycin bone and surrounding tissue concentrations have been demonstrated after tobramycin-impregnated beads were placed in animals and humans with open fractures or chronic osteomyelitis (10).
Chronic osteomyelitis, as seen in granulomatous conditions, is often much more indolent and slowly progressive.
 
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