chronic obstructive airway disease


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Related to chronic obstructive airway disease: Obstructive Lung Disease, COPD, Chronic obstructive lung disease
chronic obstructive airway disease; COAD; chronic obstructive pulmonary disease; COPD; chronic obstructive lung disease; COLD airway dysfunction (e.g. chronic bronchitis or emphysema) in cigarette smokers, or ex-smokers; presenting as type A, 'pink puffers' (breathlessness but near normal arterial oxygen and carbon dioxide levels), or type B, 'blue bloaters' (no breathlessness, but marked arterial hypoxia, carbon dioxide retention and polycythaemia)
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These vagal fibers, which mediate neurogenic bronchonconstriction and inflammation, as well as cough, have been shown to be activated by extracellular ATP in animal models in vivo, and aerosolized ATP is a potent bronchoconstrictor and cough inducer in human subjects, in particular in patients with chronic obstructive airway diseases.

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