Gilbert syndrome

(redirected from chronic intermittent juvenile jaundice)

fa·mil·i·al non·he·mo·lyt·ic jaun·dice

mild jaundice due to increased amounts of unconjugated bilirubin in the plasma without evidence of liver damage, biliary obstruction, or hemolysis; thought to be due to an inborn error of metabolism in which the excretion of bilirubin by the liver is defective, ascribed to decreased conjugation of bilirubin as a glucuronide or impaired uptake of hepatic bilirubin; autosomal dominant inheritance.

Gilbert syndrome

A benign hereditary condition (OMIM:143500) in which reduced bilirubin transferase activity results in intermittent hyperbilirubinaemia.

Gilbert syndrome

Constitutional liver dysfunction, low-grade chronic hyperbilirubinemia An inherited defect in bilirubin metabolism Clinical Jaundice, weakness, fatigue, nausea, abdominal pain. Cf Criggler-Najjar disease.


Nicholas A., French physician, 1858-1927.
Gilbert disease - Synonym(s): familial nonhemolytic jaundice
Gilbert syndrome - Synonym(s): familial nonhemolytic jaundice
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