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chronic hypoxia |
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chronic hypoxia, a usually slow, insidious reduction in tissue oxygenation resulting from gradually destructive or fibrotic lung diseases, congenital or acquired heart disorders, or chronic blood loss. The patient experiences persistent mental and physical fatigue, shows sluggish mental responses, and complains of a loss of ability to perform physical tasks. Unless treated, the condition may lead to disability. There may be some physiologic adjustment to the lack of oxygen as occurs in individuals who move from sea level to mountainous areas, where oxygen pressures are reduced. Compare acute hypoxia. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Although NE preferentially reflects SNS activation, epinephrine mainly characterizes adrenal involvement (16), suggesting differential regulation of these two components in response to acute and chronic hypoxia (17). In a study of rats, (9) researchers showed that chronic hypoxia (the same type typically seen in heart disease) induced by decreased blood flow to the brain caused a substantial drop in acetylcholine levels, as well as brain cell damage. Interaction of chronic hypoxia of moderate altitude on pulmonary hypertension complicating defect of the atrial septum. |
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