We hypothesized that all those metabolic and functional disorders contribute to CKD progression more significantly in case of chronic glomerulonephritis
as an initial form of the disease.
In the others the aetiology was: interstitial nephritis (26%), hypertensive nephrosclerosis (14%), chronic glomerulonephritis
(8%), diabetes (8%) and one patient had adult polycystic renal disease (2%).
The predominant causes of CKD were chronic glomerulonephritis
Key Words: Chronic glomerulonephritis
, xerostomia, oral tribulations, chronic renal failure.
When the cutoff value of urinary L-PGDS was set at 284 mg/mol Cr, which was the 95th percentile of the controls, the sensitivity for each renal disease was as follows: diabetic nephropathy, 74%; IgA nephropathy, 55%; membranous nephropathy, 50%; focal segmental glomerulosclerosis, 50%; chronic glomerulonephritis
, 83%; and chronic renal failure, 86%.
Out of 50 cases, 30 were of chronic glomerulonephritis, 12 of hypertensive nephrosclerosis, 6 of polycystic kidney disease and 2 were cases of obstructive uropathy.
FINAL DIADNOSIS NO OF CASES 1 CHRONIC GLOMERULONEPHRITIS 30 2 HYPERTENSIVE NEPHROSCLEROSIS 12 3 POLYCYSTIC KIDNEY DISEASE 6 5 OBSTRUCTIVE UROPATHY 2 Table-3: Comparison of Mean Serum Creatinine values in both Sample 1 Variable SERUM CREATININE SERUM CREATININE Select group = 1 Sample 2 Variable SERUM_CREATININE SERUM CREATININE Select group = 2 Sample 1 Sample 2 Sample size 50 25 Arithmetic mean 9.
The cause of CRF was diabetic nephropathy in 50, chronic glomerulonephritis in 24, chronic interstitial nephritis in 19, pyelonephritis and renovascular disease in 1 each and Ig A nephropathy in 3 and polycystic kidney disease in 2 patients.
The frequency of xerosis, pruritus, diffuse hyperpigmentation and nail changes were comparable in all groups of patients with different predisposing causes, including diabetic nephropathy, chronic glomerulonephritis and chronic interstitial nephritis.
In the medical history, she had received exploratory laparotomy with chronic ambulatory peritoneal dialytic tube implantation due to chronic glomerulonephritis
with end stage renal disease (ESRD) seven years ago and simple closure with omentum coverage due to bleeding gastric ulcer two years ago.
Spot urine samples were obtained from 41 healthy children (16 males and 25 females; age range, 0-18 years) and 41 patients (23 males and 18 females; age range, 0-19 years) with renal diseases, including nephrotic syndrome (acute and remission phases), chronic glomerulonephritis
such as IgA nephropathy and anaphylactoid purpura glomerulonephritis, renal anomaly, acute renal failure, and those with renal proximal tubular damage, including Lowe syndrome and Dent disease.
Their primary renal diseases were: chronic glomerulonephritis
(n = 14), interstitial nephritis (n = 2), acute renal failure (n = 3), adult dominant polycystic kidney disease (n = 3), hypertensive nephropathy (n = 3), diabetes mellitus (n = 1), and amyloidosis (n = 1).