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glomerulonephritis that presents with persisting proteinuria, chronic renal failure, and hypertension, of insidious onset or as a late sequel of acute glomerulonephritis; the kidneys are symmetrically contracted and granular, with scarring and loss of glomeruli and the presence of tubular atrophy and interstitial fibrosis.
Synonym(s): chronic nephritis
a noninfectious disease of the glomeruli of the kidney characterized by proteinuria, hematuria, edema, and decreased production of urine. Of unknown cause, it is asymptomatic for years. The symptoms develop slowly, and the disease progresses to kidney failure. Transplantation and dialysis are the only treatments available. See also postinfectious glomerulonephritis, subacute glomerulonephritis, uremia.