chronic glomerulonephritis


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chron·ic glo·mer·u·lo·ne·phri·tis

glomerulonephritis that presents with persisting proteinuria, chronic renal failure, and hypertension, of insidious onset or as a late sequel of acute glomerulonephritis; the kidneys are symmetrically contracted and granular, with scarring and loss of glomeruli and the presence of tubular atrophy and interstitial fibrosis.
Synonym(s): chronic nephritis

chronic glomerulonephritis

a noninfectious disease of the glomeruli of the kidney characterized by proteinuria, hematuria, edema, and decreased production of urine. Of unknown cause, it is asymptomatic for years. The symptoms develop slowly, and the disease progresses to kidney failure. Transplantation and dialysis are the only treatments available. See also postinfectious glomerulonephritis, subacute glomerulonephritis, uremia.

chronic glomerulonephritis

Chronic nephritis Nephrology An advanced kidney disease characterized by inflammation and slowly progressive renal failure Etiology Idiopathic–1/4, amyloidosis, diabetic nephropathy, focal segmental glomerulosclerosis, IgA nephropathy, lupus nephropathy, myeloma, rapidly progressive glomerulonephritis. See Diabetic nephropathy, Focal segmental glomerulosclerosis, IgA nephropathy, Lupus nephropathy, Rapidly progressive glomerulonephritis.
References in periodicals archive ?
When the cutoff value of urinary L-PGDS was set at 284 mg/mol Cr, which was the 95th percentile of the controls, the sensitivity for each renal disease was as follows: diabetic nephropathy, 74%; IgA nephropathy, 55%; membranous nephropathy, 50%; focal segmental glomerulosclerosis, 50%; chronic glomerulonephritis, 83%; and chronic renal failure, 86%.
The underlying causes of end stage renal failure were chronic glomerulonephritis (CGN; n = 68), diabetes mellitus (DM; n = 48), hypertension (n = 17), polycystic kidney disease (n = 13), lupus nephritis and vasculitis (n = 7), reflux and obstructive nephropathy (n = 5), and interstitial nephritis (n = 1; Table 1A).
Spot urine samples were obtained from 41 healthy children (16 males and 25 females; age range, 0-18 years) and 41 patients (23 males and 18 females; age range, 0-19 years) with renal diseases, including nephrotic syndrome (acute and remission phases), chronic glomerulonephritis such as IgA nephropathy and anaphylactoid purpura glomerulonephritis, renal anomaly, acute renal failure, and those with renal proximal tubular damage, including Lowe syndrome and Dent disease.
A band of 75 kDa was observed in patients with chronic glomerulonephritis and focal segmental glomerulosclerosis (FSGS; Fig.
Renal failure was caused by diabetes in 11 (46%) patients and by chronic glomerulonephritis (n = 3), polycystic kidney disease (n = 1), hypertensive nephrosclerosis (n = 6), focal glomerulosclerosis (n = 2), and poststreptococcal glomerulonephritis (n = 1).
Their primary renal diseases were: chronic glomerulonephritis (n = 14), interstitial nephritis (n = 2), acute renal failure (n = 3), adult dominant polycystic kidney disease (n = 3), hypertensive nephropathy (n = 3), diabetes mellitus (n = 1), and amyloidosis (n = 1).

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