Metaplasia is a common finding in chronic cholecystitis and is considered a precursor lesion of dysplasia.
Phospho-mTOR Expression in Chronic Cholecystitis and Advanced Gallbladder Carcinoma According to Positive Status Groups N Negative, Weak, Moderate, No.
We found that CTGF is overexpressed with significantly higher frequency in advanced tumors, showing a progressive increase from chronic cholecystitis to dysplasia and then to early and advanced carcinoma.
Our results showed that CTGF is expressed at low levels in chronic cholecystitis, suggesting a role for this protein in the inflammatory process of the gallbladder.
We found that CTGF protein levels in infiltrating gallbladder carcinoma were significantly higher than in chronic cholecystitis and dysplasia.
The pathology report confirmed that the gallbladder had features of chronic cholecystitis and the gastric mucosa was consistent with a duplication cyst that did not communicate with the gastric cavity.
This delay resulted in the development of chronic cholecystitis.