chronic hepatitis

(redirected from chronic active liver disease)
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chron·ic hep·a·ti·tis

any of several types of hepatitis persisting for longer than 6 months, often progressing to cirrhosis.

chronic hepatitis

Etymology: Gk, chronos, time, hēpar, liver, itis, inflammation
a state in which symptoms of hepatitis continue for several months and may increase in severity. In some cases of hepatitis B, the patient may become a lifelong carrier of the antigen and may show prolonged evidence of the infection. See also alcoholic hepatitis, anicteric hepatitis, cholestatic hepatitis, hepatitis, hepatitis A, hepatitis B, hepatitis C, hepatitis D, hepatitis E.

chronic hepatitis

Inflammation of the liver that does not improve within 6 months, excluding primary biliary cirrhosis, primary sclerosing cholangitis, alpha1 antitrypsin deficiency and Wilson’s disease. 

Aetiology
Autoimmune hepatitis, drug-induced hepatitis, HBV, HCV, HDV, chronic hepatitis of unknown origin (cryptogenic hepatitis).

Histologic clues for aetiology of chronic hepatitis
Viruses—Ground glass, fat, lymphoid aggregates, lymphocytosis, low grade.
Autoimmune—Plasma cells, rosetting, florid activity.
Drugs—Eosinophils, granulomas, mixed cellular reaction.

chronic hepatitis

Hepatology Inflammation of the liver that continues without improvement for ≥ 6 months. See Cirrhosis. Cf Acute hepatitis.

chron·ic hep·a·tit·is

(kronik hep-ă-tītis)
One of several types of liver disease persisting for longer than 6 months, often progressing to cirrhosis.

Chronic hepatitis

Long lasting inflammation of the liver due to viruses or other causes.

chronic hepatitis

carrier state of hepatitis B and C infections
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