EDEM2

(redirected from chromosome 20 open reading frame 31)

EDEM2

A gene on chromosome 20q11.22 that encodes a ubiqitously expressed enzyme involved in endoplasmic reticulum-associated degradation (ERAD), extracting misfolded—but not productively folded—glycoproteins from the calnexin cycle and targeting them for degradation in an N-glycan-independent manner.
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