chromosomal

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chro·mo·som·al

(krō'mō-sō'măl),
Pertaining to chromosomes.

chromosomal

chro·mo·som·al

(krōmŏ-sōmăl)
Pertaining to chromosomes.

chro·mo·som·al

(krōmŏ-sōmăl)
Pertaining to chromosomes.

chromosomal,

adj relating to chromosome, or a configuration within the cell's nucleus that contains a linear thread of DNA that conveys genetic data.

chromosomal

emanating from or pertaining to chromosome.

chromosomal aberration
see chromosomal abnormality (below).
chromosomal abnormality
abnormal karyotype; abnormalities can be detected before birth by means of amniocentesis, or after birth, but many are probably never observed because they cause death and disposal of the fetus. The abnormalities are either of number, or of composition of the individual chromosomes. Monosomy and trisomy are examples of numerical abnormalities. Translocations are examples of abnormalities of structure where parts of one chromosome have been transferred to another. The cause of these abnormalities is not known. Their importance is that many of them are linked with structural or functional defects of the animal body. The best known ones in veterinary medicine are those that are related to infertility, e.g. translocation 1/29, translocation 27/29.
chromosomal analysis
fetal cells obtained by amniocentesis or lymphocytes from a blood sample can be cultured in the laboratory until they divide. Cell division is arrested in mid-metaphase by the drug Colcemid, a derivative of colchicine. The chromosomes can be stained by one of several techniques that produce a distinct pattern of light and dark bands along the chromosomes, and each chromosome can be recognized by its size and banding pattern. The chromosomal characteristics of an animal are referred to as its karyotype. This also refers to a photomicrograph of a cell nucleus that is cut apart and rearranged so that the individual chromosomes are in order and labeled. The autosomes are numbered roughly in order of decreasing length. The sex chromosomes are labeled X and Y. Karyotyping is useful in determining the presence of chromosome defects.
chromosomal banding
see banding (2).
chromosomal chimerism
see chimera.
chromosomal crossover
chromosomal deletion
in genetics, loss from a chromosome of genetic material.
chromosomal inversion
see inversion (2).
chromosomal linkage
see linkage (2).
chromosomal mapping
see genetic map.
chromosomal non-disjunction
failure of the chromatids or chromosomes to separate (disjoin) during meiosis.
chromosomal replication
chromosomal walking
a technique for identification and isolation of contiguous sequences of genomic DNA.
chromosomal X inactivation
only one of a pair of female (X) chromosomes in the one cell is active, the other is inactivated.
References in periodicals archive ?
Liu J, Cavalli LR, Haddad BR, Papadopoulos V (2003) Molecular cloning, genomic organization, chromosomal mapping and subcellular localization of mouse PAP7: a PBR and PKA-RI(alpha) associated protein.
Equally important, the system will support a wide range of additional genotyping applications, such as linkage analysis and fine chromosomal mapping, to help the Canadian genomics community contribute materially to an improved global understanding of genetic variation and function.
Chromosomal mapping of genes and DNA fragments are important for the identification of chromosomes, which has been difficult in marine bivalves.
Here we report the chromosomal mapping of the major rRNA genes in the dwarf surfclam, M.
FISH offers a powerful tool not only for chromosome identification but also for a range of genomic analyses, including the chromosomal mapping of genes (Swiger & Tucker 1996).
Although chromosome identification is essential in chromosomal mapping and studies on aneuploidy and chromosomal rearrangements, it remains a major challenge in oysters and other marine molluscs because traditional karyotyping cannot distinguish all oyster chromosomes.
Unlike current technologies utilized by chromosomal mapping or high-throughput cDNA sequencing companies, DGT's technology utilizes a novel approach to the survey of mRNA, for the first time resulting in a complete catalogue of the identities and expression patterns of all genes expressed in any cell or tissue sample.
a chromosomal mapping company focused on the human genome, in undertaking an initial public offering.