chromosomal instability syndrome


Also found in: Encyclopedia, Wikipedia.

chromosomal instability syndrome

n.
Any of a group of Mendelian inheritance conditions associated with chromosomal instability and breakage in vitro and often leading to an increased tendency to develop certain types of malignancies. Also called chromosomal breakage syndrome.
References in periodicals archive ?
The naevoid basal-cell carcinoma syndrome (Gorlin syndrome) is a chromosomal instability syndrome, Mutat Res 397:287-292.