chromosomal instability syndromes

(redirected from chromosomal breakage syndromes)

chro·mo·som·al in·sta·bil·i·ty syn·dromes

, chromosomal breakage syndromes
a group of mendelian conditions associated with chromosomal instability and breakage in vitro, they often manifest an increased tendency to certain types of malignancies. See: Bloom syndrome, xeroderma pigmentosum.

chro·mo·som·al in·sta·bil·i·ty syn·dromes

, chromosomal breakage syndromes (krō'mŏ-sŏ'măl in'stă-bil'i-tē sin'drōmz, krō'mŏ-sŏ'măl brāk'ăj sin'drōmz)
A group of mendelian conditions associated with chromosomal instability and breakage in vitro. They often manifest an increased tendency to certain types of malignancies.
See: fragile X chromosome, xeroderma pigmentosum