chromosomal

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Related to chromosomal analysis: karyotyping, Chromosomal abnormalities

chro·mo·som·al

(krō'mō-sō'măl),
Pertaining to chromosomes.

chromosomal

chro·mo·som·al

(krōmŏ-sōmăl)
Pertaining to chromosomes.

chro·mo·som·al

(krōmŏ-sōmăl)
Pertaining to chromosomes.

chromosomal,

adj relating to chromosome, or a configuration within the cell's nucleus that contains a linear thread of DNA that conveys genetic data.

chromosomal

emanating from or pertaining to chromosome.

chromosomal aberration
see chromosomal abnormality (below).
chromosomal abnormality
abnormal karyotype; abnormalities can be detected before birth by means of amniocentesis, or after birth, but many are probably never observed because they cause death and disposal of the fetus. The abnormalities are either of number, or of composition of the individual chromosomes. Monosomy and trisomy are examples of numerical abnormalities. Translocations are examples of abnormalities of structure where parts of one chromosome have been transferred to another. The cause of these abnormalities is not known. Their importance is that many of them are linked with structural or functional defects of the animal body. The best known ones in veterinary medicine are those that are related to infertility, e.g. translocation 1/29, translocation 27/29.
chromosomal analysis
fetal cells obtained by amniocentesis or lymphocytes from a blood sample can be cultured in the laboratory until they divide. Cell division is arrested in mid-metaphase by the drug Colcemid, a derivative of colchicine. The chromosomes can be stained by one of several techniques that produce a distinct pattern of light and dark bands along the chromosomes, and each chromosome can be recognized by its size and banding pattern. The chromosomal characteristics of an animal are referred to as its karyotype. This also refers to a photomicrograph of a cell nucleus that is cut apart and rearranged so that the individual chromosomes are in order and labeled. The autosomes are numbered roughly in order of decreasing length. The sex chromosomes are labeled X and Y. Karyotyping is useful in determining the presence of chromosome defects.
chromosomal banding
see banding (2).
chromosomal chimerism
see chimera.
chromosomal crossover
chromosomal deletion
in genetics, loss from a chromosome of genetic material.
chromosomal inversion
see inversion (2).
chromosomal linkage
see linkage (2).
chromosomal mapping
see genetic map.
chromosomal non-disjunction
failure of the chromatids or chromosomes to separate (disjoin) during meiosis.
chromosomal replication
chromosomal walking
a technique for identification and isolation of contiguous sequences of genomic DNA.
chromosomal X inactivation
only one of a pair of female (X) chromosomes in the one cell is active, the other is inactivated.
References in periodicals archive ?
The growing number of genetic tests has been made possible by advances in technology, including advances in chromosomal analysis - from traditional karyotyping to fluorescence in situ hybridization (FISH), and then to chromosomal microarrays and next generation sequencing.
In RM cases, the parental chromosomal analysis plays a significant role as the cause of the RM can be understood.
Chromosomal analysis was completed prenatally or at the time of ultrasonography, diagnosing demise for 14.
Chromosomal analysis on peripheral blood was planned because of the dysmorphic characteristics, epilepsy and mental retardation.
Comparative chromosomal analysis and phylogeny in four Ctenomys species (Rodentia, Octodontidae).
Chromosomal analysis of affected patients has consistently revealed a normal karyotype.
DVM, PhD, principal investigator) -- $669,000 for the first year of funding to create a central core facility to provide cell tissue culture support, including media preparation, quality control and routine chromosomal analysis of cultured stem cells.
Chromosomal analysis and health status of children conceived to men during or following dibromochloropropane-induced spermatogenic depression.
The immunohistochemical techniques and chromosomal analysis methods that are currently available are discussed.
But full chromosomal analysis has not been possible as existing technology has limited analysis to a small number of chromosomes per cell.
We look forward to the progression from the already impressive CA 850 to CMDX's new CA 1000 microarray for clinical chromosomal analysis.