chromophobe adenoma

adenoma /ad·e·no·ma/ (ad″ĕ-no´mah) a benign epithelial tumor in which the cells form recognizable glandular structures or in which the cells are derived from glandular epithelium.

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adrenocortical adenoma  a benign tumor of the adrenal cortex, usually small and unilateral; most types cause endocrine symptoms.

basal cell adenoma  a benign, encapsulated, slow-growing, painless salivary gland tumor of intercalated or reserve cell origin, occurring mainly in males, in the parotid gland or upper lip; solid, canalicular, trabecular-tubular, and membranous types can be distinguished histologically.

bile duct adenoma  a small firm white nodule with multiple bile ducts embedded in a fibrous stroma.

bronchial adenomas  tumors of low-grade malignancy situated in the submucosal tissues of large bronchi; sometimes composed of well-differentiated cells and usually circumscribed, with two histologic forms: carcinoid and cylindroma.

carcinoma ex pleomorphic adenoma  see under carcinoma .

chromophobe adenoma , chromophobic adenoma null-cell a.

corticotroph adenoma  a pituitary adenoma made up predominantly of corticotrophs and secreting excess corticotropin.

follicular adenoma  adenoma of the thyroid in which the cells are arranged in the form of follicles.

glycoprotein adenoma  a pituitary adenoma that causes excessive secretion of one of the three glycoprotein hormones (follicle-stimulating hormone, luteinizing hormone, and thyrotropin).

hepatocellular adenoma  a benign circumscribed tumor of the liver, usually in the right lobe, growing in a sheetlike fashion; it may be highly vascular with a tendency to hemorrhage and with areas of necrosis.

Hürthle cell adenoma  see under tumor.

liver cell adenoma  hepatocellular a.

macrofollicular adenoma  a follicular adenoma composed of large follicles filled with colloid and lined with flat epithelium.

microfollicular adenoma  a follicular adenoma with small, closely-packed follicles lined with epithelium.

mixed-cell adenoma  a pituitary adenoma containing more than one cell type, usually making it plurihormonal.

monomorphic adenoma  any of a group of benign salivary gland tumors that lack connective tissue changes and are each predominantly composed of a single cell type.

nipple adenoma  a benign lesion of the breast, clinically resembling Paget's disease of the breast, consisting of ductal and stromal proliferation beneath the nipple, which presents as a mass, ulceration, or erosion, with a serous or bloody discharge.

null-cell adenoma  a pituitary adenoma whose cells give negative results on tests for staining and hormone secretion, although some may contain functioning cells and be associated with a hyperpituitary state.

oncocytic adenoma , oxyphilic adenoma

1. oncocytoma.

2. Hürthle cell adenoma.

papillary adenoma  nipple a..

papillary cystic adenoma  papillary cystadenoma.

pituitary adenoma  a benign neoplasm of the anterior pituitary gland; the endocrine-active a's contain cells that secrete anterior pituitary hormones; the endocrine-inactive a's are not secretory.

pleomorphic adenoma  a benign, slow-growing, epithelial tumor of the salivary gland, usually of the parotid gland, sometimes serving as a locus for development of a malignant epithelial neoplasm (malignant pleomorphic a.) .

plurihormonal adenoma  an endocrine-active adenoma that secretes two or more hormones, usually growth hormone and one or more of the glycoprotein types.

sebaceous adenoma 

1. an uncommon, benign, yellow or flesh-colored, circumscribed nodule occurring on the face or scalp, generally in older men, consisting of incompletely differentiated sebaceous lobules.

2. a. sebaceum.

adenoma seba´ceum 

1. cutaneous angiofibromatous proliferation, usually on the face, in association with tuberous sclerosis.

2. nevoid hyperplasia of sebaceous glands, forming multiple yellow papules or nodules of the face.

trabecular adenoma  a follicular adenoma whose cells are closely packed to form cords or trabeculae, with only a few small follicles.

tubular adenoma 

1. an adenoma whose cells are arranged in tubules.

2. androblastoma (1).

3. the most common type of adenomatous polyp of the colon, with tubules highly variable in size and often occurring singly.

villous adenoma  an uncommon type of adenomatous polyp of the colon that is large, soft, and papillary and often premalignant.

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chromophobe adenoma

n.

An adenoma of the chromophobe cells of the anterior pituitary gland.

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chromophobe adenoma.

See chromophobic adenoma.

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chromophobe

any cell, structure or tissue that does not stain readily; applied especially to the chromophobe cells of the anterior lobe of the pituitary gland.

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chromophobe adenoma

a nonfunctional pituitary tumor of the pars distalis is hormonally inactive but commonly causes clinical signs by compression of the pituitary gland and other nearby structures. Clinical signs include incoordination, weakness and exercise intolerance, muscle atrophy, sexual inactivity, blindness and dilatation and fixation of the pupils.

chromophobe carcinoma

rare nonfunctional pituitary tumors are usually large and invasive causing destruction of the pars distalis leading to panhypopituitarism and diabetes insipidus. There is extensive invasion of the brain and cranial bones, and metastases to spleen and liver and to regional lymph nodes may occur.