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chromophobe

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.01 sec.
chromophobe /chro·mo·phobe/ (-fōb) any cell or tissue not readily stainable, such as the chromophobe cells in the adenohypophysis.
chro·mo·phobe (krm-fb) or chro·mo·pho·bic (krm-fbk)
adj.
Resistant to stains; staining with difficulty or not at all.
n.
A cell that is resistant to stains.

chromophobe.
chromophobe [kro´mo-fōb]
any cell, structure, or tissue that does not stain readily; applied especially to the chromophobe cells of the anterior lobe of the pituitary gland.

chromophobe
any cell, structure or tissue that does not stain readily; applied especially to the chromophobe cells of the anterior lobe of the pituitary gland.

chromophobe adenoma
a nonfunctional pituitary tumor of the pars distalis is hormonally inactive but commonly causes clinical signs by compression of the pituitary gland and other nearby structures. Clinical signs include incoordination, weakness and exercise intolerance, muscle atrophy, sexual inactivity, blindness and dilatation and fixation of the pupils.
chromophobe carcinoma
rare nonfunctional pituitary tumors are usually large and invasive causing destruction of the pars distalis leading to panhypopituitarism and diabetes insipidus. There is extensive invasion of the brain and cranial bones, and metastases to spleen and liver and to regional lymph nodes may occur.


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Previously, pathologic analysis could not distinguish a benign oncocytoma from a chromophobe subtype of RCC since oncocytic cells are seen in both lesions.
Sarcomatoid change represents a high-grade transformation or dedifferentiation in any of the classical variants of renal cell carcinoma (RCC), including chromophobe RCC, and is not a distinct histologic entity.
 
 
 
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