papillary renal cell carcinoma(redirected from chromophil renal cell carcinoma)
papillary renal cell carcinoma
the second most common form of renal cell carcinoma, accounting for approximately 15% of all renal malignancies; histologically similar to papillary carcinomas in other organs. Histogenetically and genetically, it is distinct from clear cell renal carcinoma. It is found in 80% of people who have a tuberous sclerosis.
Synonym(s): chromophil renal cell carcinoma
PRCCA gene on chromosome 1q21.1 that encodes a protein thought to play a role in pre-mRNA splicing.
PRCC translocation (X;1)(p11;q21) to TFE3 is associated with papillary renal cell carcinoma.