papillary renal cell carcinoma

(redirected from chromophil renal cell carcinoma)

papillary renal cell carcinoma

the second most common form of renal cell carcinoma, accounting for approximately 15% of all renal malignancies; histologically similar to papillary carcinomas in other organs. Histogenetically and genetically, it is distinct from clear cell renal carcinoma. It is found in 80% of people who have a tuberous sclerosis.

PRCC

A gene on chromosome 1q21.1 that encodes a protein thought to play a role in pre-mRNA splicing.

Molecular pathology
PRCC translocation (X;1)(p11;q21) to TFE3 is associated with papillary renal cell carcinoma.
References in periodicals archive ?
Typical chromophobe and chromophil renal cell carcinomas also contain such vesicles, but to a much lesser extent.