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chromaffin cell

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chromaffin cell
n.
A cell that stains readily with chromium salts, especially a cell of the adrenal medulla.

chromaffin cell,
any one of the special cells that compose the paraganglia and are connected to the ganglia of the celiac, renal, suprarenal, aortic, and hypogastric plexuses. The chromaffin cells of the adrenal medulla secrete two catecholamines, epinephrine and norepinephrine, which affect smooth muscle, cardiac muscle, and glands in the same way as sympathetic stimulation, by increasing and prolonging sympathetic effects.


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Certain reports contend that this chromaffin cell therapy approach would have had problems clinically [26] with or without the clinically tested microencapsulation [27] that surrounded the grafts to prevent immune rejection [28].
In the second stage, beginning 48 hours after the injury, the adrenals are greatly enlarged but regain their lipoid granules, while the medullary chromaffin cells show vacuolization; the edema begins to disappear, numerous basophiles appear in the pituitary; the thyroid shows a tendency towards hyperplasia (more marked in the guinea pig); general body growth ceases, and the gonads become atrophic; in lactating animals, milk secretion stops.
A primary response is the activation of brain centers, which eventually results in the release of cortisol from the steroid-producing cells and of catecholamines from the head kidney chromaffin cells.
 
 
 
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