chordoma


Also found in: Dictionary, Acronyms, Encyclopedia, Wikipedia.

chordoma

 [kor-do´mah]
a malignant tumor arising in the axial skeleton from embryonic remains of the notochord.

chor·do·ma

(kōr-dō'mă), [MIM*215400]
A rare neoplasm of skeletal tissue in adults, derived from persistent portions of the notochord; composed of cells arranged in lobules, with abundant myxoid stroma; some cells contain vacuoles that resemble soap bubbles (physaliphorous cells); most frequently in the region of the clivus or lumbar-sacral cord.
[(noto)chord + G. -oma, tumor]

chordoma

/chor·do·ma/ (kor-do´mah) a malignant tumor arising from the embryonic remains of the notochord.

chordoma

[kôrdō′mə] pl. chordomas, chordomata,
a rare tumor that develops from the fetal notochord. It is usually located in the midline, behind the sella; it is slow growing but highly invasive.

chordoma

An encapsulated, locally invasive malignant tumour that arises from the foetal notochord in the sacrococcygeal and sphenooccipital regions.
 
Epidemiology
Predominantly in older (age 50–70) men for sacrococcygeal region and age 20–40 for sphenooccipital chordoma.
 
Management
Surgery, RT.
 
Prognosis
Recurrence is common, often years after adequate therapy.

chor·do·ma

(kōr-dō'mă)
A rare neoplasm of skeletal tissue in adults, derived from persistent portions of the notochord.
[(noto)chord + G. -oma, tumor]

chordoma

A slow-growing tumour of the spine arising from remnants of the primitive NOTOCHORD. Chordomas rarely spread remotely, but can cause severe local damage.

chordoma

a malignant tumor arising from embryonic remains of the notochord.
References in periodicals archive ?
Munzenrider and Liebsch found that among the patients who had skull base tumors, local recurrence-free survival at 10 years was significantly higher among those who had chondrosarcomas than those who had chordomas (94 vs 54%; p[less than]0.
It is extremely rare for chordoma to present in a lumbar vertebral body and this case report highlights an unusual presentation of spinal pathology.
The radiologic work-up for sacral chordoma includes radiography, CT, and magnetic resonance (MR) imaging.
Wippold, Koeller, and Smirniotopoulos (1998) attempted to define the clinical and imaging features of a series of 10 patients with cervical chordoma.
Clival chordomas are rare tumors near the base of the brain and skull that can be difficult to treat with standard radiation therapy," explained Dr.
Chondrosarcoma of the base of the skull: A clinicopathologic study of 200 cases with emphasis on its distinction from chordoma.
Past medical history was significant for clival chordoma resection and removal of a thyroglossal duct cyst.
2-7) In this case report, we describe a case of clival chordoma that at presentation had gone undiagnosed and therefore untreated for an extended period of time.
Related nursing considerations for the patient undergoing a maxillotomy for resection of a clival chordoma are included.
Currently, a chordoid meningioma is considered to be a "meningioma variant consisting predominantly of tissue histologically similar to chordoma.
Josh Sommer, Executive Director of the Chordoma Foundation, agreed with the potential promise of the Initiative, noting: "As a patient group ourselves, we can't afford to fund anything but research that is reproducible and robust enough to be developed into new therapies.
The main differential diagnoses include chordoma and chondrosarcoma with myxoid features.