chondroitinase

chondroitinase

(1) N-Acetylgalactosamine-6-sulfatase, EC 3.1.6.4 (N-Acetyl-d-galactosamine-6-sulfate 6-sulfohydrolase). 
(2) N-Acetylgalactosamine-4-sulfatase, EC 3.1.6.12 (N-Acetyl-d-galactosamine-4-sulfate 4-sulfohydrolase). 
(3) Hyaluronoglucosaminidase, EC 3.2.1.35 (hyaluronate 4-glycanohydrolase).
(4) Chondroitin ABC lyase,  EC 4.2.2.4. 
(5) Chondroitin AC lyase, EC 4.2.2.5.
References in periodicals archive ?
Past research suggested one way to promote the growth of injured spinal nerve cells was to administer an enzyme known as chondroitinase ABC (ChABC), which digests scar-forming proteins.
Building on a technique developed by her colleagues at Case Western Reserve University in Cleveland, Warren injected an enzyme called chondroitinase ABC into the rats' spinal cords to clear out scar tissue a year and a half after the injury.
Chondroitinase ABC promotes functional recovery after spinal cord injury.
Chondroitinase, an enzyme that encourages nerve plasticity in spinal cord injury, is in preclinical development.
They also reported that, when these mice were given a drug called chondroitinase ABC, fear memories were more likely to disappear than for those mice in the control group.
The team has found that a bacterial enzyme called chondroitinase can digest molecules within scar tissue to allow some nerve fibres to regrow It also promotes nerve plasticity, which means that any remaining undamaged nerve fibres have an increased likelihood of making new connections to bypass the area of damage.
BioMarin's pipeline of products for non-pediatric diseases will be commercialized by partners While the company's commercial focus is concentrated in the pediatric field, it plans on having partners continue the development and initiate commercialization efforts for its novel non-pediatric biologics and platform technologies, including Vibrilase for burns and wounds, Chondroitinase for spinal cord injury, and NeuroTrans for delivering proteins across the blood-brain barrier.
Some cultures were treated with chondroitinase ABC, an enzyme that digest chondroitin sulfate chains.
Using a compound called chondroitinase ABC to dissolve components of perineuronal nets, which hold nerve cells in place, improves visual acuity.
We incubated 10 [micro]L of urinary extract with 25 mU of chondroitinase ABC in 50 mmol/L Tris-HCI buffer (pH 8.
Biomechanical properties of normal tendons, normal palmar aponeuroses and tissues from patients with Dupuytren's contracture subjected to elastase and chondroitinase treatment.