ACAN

(redirected from chondroitin sulfate proteoglycan 1)

ACAN

A gene on chromosome 15q26.1 that encodes an aggrecan/versican proteoglycan, which is an integral part of the extracellular matrix in cartilage, where it provides compressive resistance.

Molecular pathology
ACAN mutations occur in skeletal dysplasia and spinal degeneration.
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