chondroblastoma


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chondroblastoma

 [kon″dro-blas-to´mah]
a benign tumor arising from young chondroblasts in the epiphysis of a bone.

chon·dro·blas·to·ma

(kon'drō-blas-tō'mă),
A benign tumor arising in the epiphyses of long bones, consisting of highly cellular tissue resembling fetal cartilage.

chondroblastoma

/chon·dro·blas·to·ma/ (kon″dro-blas-to´mah) a usually benign tumor derived from immature cartilage cells, occurring primarily in the epiphyses of adolescents.

chondroblastoma

[kon′drōblastō′mə] pl. chondroblastomas, chondroblastomata,
a benign tumor, derived from precursors of cartilage cells, that develops most frequently in epiphyses of the femur and humerus, especially in young men. The lesions may contain scattered areas of calcification and necrosis. Also called Codman's tumor.

chondroblastoma

A benign tumour that arises in the epiphysis or in secondary ossification centres of long bones (humerus, proximal and distal femur, proximal tibia) of young adults (< age 30).

Imaging
Well-defined lytic lesion with a fluffy cotton-wool appearance, ± sclerotic border.

chon·dro·blas·to·ma

(kon'drō-blas-tō'mă)
A benign tumor arising in the epiphyses of long bones, consisting of highly cellular tissue resembling fetal cartilage.

chondroblastoma

uncommon, painful or asymptomatic benign bone lesion of knee, talus and calcaneum, presenting on radiograph as a clearly defined round or oval bone lesion with a sclerotic border (see Table 1)
Table 1: Tumours arising in bone
Bone tumour typeExamples occurring in lower limb/foot
BenignAneurysmal bone cyst
Solitary osteochondroma
Simple/solitary bone cyst
Osteoid osteoma
Giant-cell tumour
Enchondroma
Chondroblastoma
MalignantChondrosarcoma
Ewing's sarcoma
Osteogenic sarcoma

chondroblastoma

a benign tumor arising from young chondroblasts in the epiphysis of a bone.
References in periodicals archive ?
Differential diagnosis for lesions that centered within the thyroid or crycoid cartilage includes giant cell reparative granuloma, brown tumor of hyperparathyroidism, osteoblastoma, chondroblastoma, chondrosarcoma, chondroma, aneurysmal bone cyst, nonossifying fibroma, foreign body reaction, benign fibrous histiocytoma, malignant fibrous histiocytoma, osteosarcoma with abundant giant cells, and carcinoma (including spindle cell or sarcomatoid carcinoma) with giant cells.
15,18) Primary lesions most frequently associated with ABC (in order of frequency) include giant cell tumor of bone, chondroblastoma, chondromyxoid fibroma, and fibrous dysplasia, particularly in pregnancy.
13) GCRG must be differentiated from the brown tumor of hyperparathyroidism, aneurysmal bone cyst, chondroblastoma, fibrous dysplasia, cherubism, osteosarcoma, and true giant-cell tumor.
The differential diagnosis includes an eurysmal bone cysts, chondroblastoma, chondromyxoid fibroma, giant cell reparative granuloma, nonossifying fibroma, Langerhans' cell histiocytosis, synovial sarcoma, and high-grade central osteosarcoma.
These include aneurysmal bone cyst, chondroblastoma, nonossifying fibroma, giant cell reparative granuloma, pigmented villonodular synovitis, giant cell tumor of tendon sheath, and giant cell-rich osteosarcoma.
Reported tumors include chondroblastoma, histiocytosis, giant cell tumor, simple bone cyst, brown tumor of hyperparathyroidism, hemangioma, osteochondroma, lipoma, and osteoblastoma.
Brachyury staining was further performed in the following 2 categories: (1) 58 nonchordomatous tumors, which included 26 chondroid tumors (4 cases of grade I chondrosarcoma, 9 cases of grade II chondrosarcoma, 3 cases of grade III chondrosarcoma, 2 cases of chondromyxoid fibroma, 1 chondroblastoma, 4 osteochondromas, and 2 cases of extraskeletal myxoid chondrosarcoma), 7 liposarcomas, 5 rhabdomyosarcomas, 4 pleomorphic adenomas, 4 mucoepidermoid carcinomas, 4 mucinous adenocarcinomas, 6 germ cell tumors, and 2 cases of renal cell carcinoma (Table 2); and (2) 7 unrelated miscellaneous tissues, which included normal cartilage derived from trachea (2 cases), articular surface (1 case), and testicular tissue (4 cases).
This constellation of imaging features is helpful in differentiating an intraosseous ganglion from other radiolucent epiphyseal lesions such as chondroblastoma, giant cell tumor, simple bone cyst, clear cell chondrosarcoma (in older patients), and subchondral cyst or geode, which occurs in the setting of arthritis.
Epithelioid and epithelial neoplasms seen in bone are rare and include epithelioid variants of vascular lesions, osteoblastoma, osteosarcoma, chordoma, and chondroblastoma as well as adamantinoma and metastatic carcinoma.
Primary treatment of chondroblastoma with percutaneous radio-frequency heat ablation: Report of three cases.
The differential diagnosis for this cytomorphologically benign lesion included villonodular synovitis, giant cell reparative granuloma, and benign chondroblastoma.
Neoplasms that may occur in the occipital bone include such diverse entities as chondroblastoma, ossifying fibroma, atypical juvenile xanthogranuloma of childhood, epidermoid tumor, giant cell tumor in the background of von Recklinghausen disease, melanotic neuroectodermal tumor of infancy, and primary lymphoma.