cholinergic

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Related to cholinergic neurotransmission: acetylcholine, cholinergic neurotransmitter

cholinergic

 [ko″lin-er´jik]
1. activated or transmitted by acetylcholine; see also cholinergic fibers and cholinergic receptors.
2. an agent that resembles acetylcholine or simulates its action. Called also parasympathomimetic.

cho·lin·er·gic

(kōl'in-er'jik),
Relating to nerve cells or fibers that use acetylcholine as their neurotransmitter. Compare: adrenergic.
[choline + G. ergon, work]

cholinergic

/cho·lin·er·gic/ (ko″lin-er´jik)
1. parasympathomimetic; stimulated, activated, or transmitted by choline (acetylcholine); said of the sympathetic and parasympathetic nerve fibers that liberate acetylcholine at a synapse when a nerve impulse passes.
2. an agent that produces such an effect.

cholinergic

(kō′lə-nûr′jĭk)
adj.
1. Activated by or capable of liberating acetylcholine, especially in the parasympathetic nervous system.
2. Having physiological effects similar to those of acetylcholine: a cholinergic agent or drug.

cho′li·ner′gi·cal·ly adv.

cholinergic

[-ur′jik]
Etymology: Gk, chole + ergon, to work
1 pertaining to nerve fibers that liberate acetylcholine at the myoneural junctions.
2 the tendency to transmit or to be stimulated by or to stimulate the elaboration of acetylcholine. Also called cholinergic stimulant. Compare adrenergic, anticholinergic.

cholinergic

Pharmacology adjective Referring to a parasympathomimetic effect, specifically on cholinergic receptors, evoking acetylcholine release noun A chemical or drug–eg, bethanechol, that stimulates acetylcholine release from parasympathetic nerve endings. See Parasympathetic nervous system. See Cholinergic crisis. Cf Adrenergic.

cho·lin·er·gic

(kōli-nĕrjik)
Relating to nerve cells or fibers that employ acetylcholine as their neurotransmitter.
Compare: adrenergic
[choline + G. ergon, work]

cholinergic

1. Pertaining to nerves that release ACETYLCHOLINE at their endings, including the nerves to the voluntary muscles and all the PARASYMPATHETIC nerves.
2. Having effects similar to those of acetylcholine.

cholinergic

(of nerve fibres) secreting ACETYLCHOLINE as a TRANSMITTER SUBSTANCE; in vertebrates these include motor fibres to STRIATED MUSCLE, parasympathetic fibres to INVOLUNTARY MUSCLE and fibres to sympathetic ganglia from the central nervous system. Compare ADRENERGIC.

Cholinergic

Nerves that are stimulated by acetylcholine.
Mentioned in: Cholinergic Drugs

cholinergic

acetylcholine-secreting nerve endings (e.g. presynaptic autonomic and postsynaptic parasympathetic nerve endings), or an agent mimicking acetylcholine release

cholinergic (kōˈ·l·nerˑ·jik),

adj pertaining to the parasympathetic part of the autonomic nervous system as well as acetylcholine release and its role as a transmitter agent.

cholinergic 

Relates to neurons or nerve fibres in which acetylcholine (ACh) is the neurotransmitter, or have actions similar to those caused by ACh. Cholinergic receptors are of two types: nicotinic receptors, which are situated in striated muscles (e.g. the extraocular muscles) and muscarinic receptors, which are situated in parasympathetically innervated structures (e.g. the iris and ciliary body). See acetylcholine; nicotine; parasympathomimetic drug.

cho·lin·er·gic

(kōli-nĕrjik)
1. Relating to nerve cells or fibers that use acetylcholine as their neurotransmitter.
2. Drug or chemical with physiologic effects similar to those of acetylcholine.
[choline + G. ergon, work]

cholinergic (parasympathomime-tic) (kō´linur´jik),

adj producing or simulating the effects of acetylcholine.
cholinergic blocking agent,
n See agent, blocking, cholinergic.
cholinergic crisis, in myasthenia gravis,
n a medical condition resulting from an administration of too much anticholinesterase, indicated by an immediate increase in muscle weakness, excessive secretion of pulmonary matter, diarrhea, and cramps.

cholinergic

1. parasympathomimetic; activated or transmitted by acetylcholine; said of nerve fibers that liberate acetylcholine at a synapse when a nerve impulse passes, i.e. the parasympathetic fibers.
2. an agent that resembles acetylcholine or simulates its action.

cholinergic blockade
selective inhibition of cholinergic nerve impulses at autonomic ganglionic synapses, postganglionic parasympathetic effectors, or neuromuscular junctions.
cholinergic neurotransmission
that form of neurotransmission which depends on the production of acetylcholine at synapses.
cholinergic receptors
receptor sites on effector organs or at nerve synapses that are stimulated by acetylcholine released by the nerve terminal. There are two types: muscarinic receptors, present primarily on autonomic effector cells, and nicotinic receptors, present primarily on autonomic ganglion cells and on the motor end plates of skeletal muscle.
References in periodicals archive ?
In detail, the gills of the organisms collected from the southernmost subbasin (site B) showed (1) histomorphological alterations attributable to inflammatory processes and regressive structural changes, (2) a compromised cholinergic neurotransmission, (3) a stimulation of the antioxidant defense system, and (4) onset of hypoxic adaptive responses.
Our results support the notion that cholinergic neurotransmission plays an important role in sustaining PS after an enriched/stressful experience, with special significance for learning and memory.
This dysfunction could be related to deficits in cholinergic neurotransmissions and their manifestation in damaged facial muscles.
Attempting to understand this effect led us to propose that IT and indeed the variance that IT shares with IQ was predominantly mediated by cholinergic neurotransmission (Stough et al.
Therefore, we speculate that PA exerts neuroprotective effects, at least in part, by increasing cholinergic neurotransmission and decreasing neuroinflammation and oxidative stress.
Donepezil is a piperidine-based drug that improves cholinergic neurotransmission by inhibiting acetylcholinesterase, he said.
Deficits in cholinergic neurotransmission, in particular a reduced number of nicotinic receptors, are an important contributor to the cognitive impairment that is typical with Alzheimer's dementia -- a disease that afflicts an estimated 15 million individuals worldwide.
This study provides definitive proof of meaningful anticholinesterase activity compatible with the observed promnesic and anti-amnesic effects of POEE in mice, reaffirming the potential of this extract for treating neurodegenerative conditions where a hypofunctioning cholinergic neurotransmission is prominent.