cholinergic blockade


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blockade

 [blok-ād´]
1. in pharmacology, the blocking of the effect of a neurotransmitter or hormone by a drug.
2. in histochemistry, a chemical reaction that modifies certain chemical groups and blocks a specific staining method.
adrenergic blockade selective inhibition of the response to sympathetic impulses transmitted by epinephrine or norepinephrine at alpha or beta receptor sites of an effector organ or postganglionic adrenergic neuron. See also adrenergic blocking agent.
cholinergic blockade selective inhibition of cholinergic nerve impulses at autonomic ganglionic synapses, postganglionic parasympathetic effectors, or neuromuscular junctions. See also cholinergic blocking agent.
ganglionic blockade inhibition by drugs of nerve impulse transmission at autonomic ganglionic synapses; see also ganglionic blocking agent.
narcotic blockade inhibition of the euphoric effects of narcotic drugs by the use of other drugs, such as methadone, in the treatment of addiction.
neuromuscular blockade a failure in neuromuscular transmission that can be induced pharmacologically or result from any of various disturbances at the myoneural junction. See also neuromuscular blocking agent.
sympathetic blockade block of nerve impulse transmission between a preganglionic sympathetic fiber and the ganglion cell.

cho·lin·er·gic block·ade

1. inhibition by a drug of nerve impulse transmission at autonomic ganglionic synapses (ganglionic blockade), at postganglionic parasympathetic effector cells (for example, by atropine), and at myoneural junctions (myoneural blockade);
2. inhibition of a cholinergic agent.

cho·lin·er·gic block·ade

(kō'lin-ĕr'jik blok-ād')
1. Inhibition by a drug of nerve impulse transmission at autonomic ganglionic synapses (ganglionic blockade), at postganglionic parasympathetic effector cells (e.g., by atropine), and at myoneural junctions (myoneural blockade).
2. The inhibition of a cholinergic agent.

blockade

1. in pharmacology, the blocking of the effect of a neurotransmitter or hormone by a drug.
2. in histochemistry, a chemical reaction that modifies certain chemical groups and blocks a specific staining method.

adrenergic blockade
see adrenergic blockade.
cholinergic blockade
see cholinergic blockade.
narcotic blockade
inhibition of the euphoric effects of narcotic drugs by the use of other drugs, such as methadone, in the treatment of addiction.
sympathetic blockade
block of nerve impulse transmission between a preganglionic sympathetic fiber and the ganglion cell.

cholinergic

1. parasympathomimetic; activated or transmitted by acetylcholine; said of nerve fibers that liberate acetylcholine at a synapse when a nerve impulse passes, i.e. the parasympathetic fibers.
2. an agent that resembles acetylcholine or simulates its action.

cholinergic blockade
selective inhibition of cholinergic nerve impulses at autonomic ganglionic synapses, postganglionic parasympathetic effectors, or neuromuscular junctions.
cholinergic neurotransmission
that form of neurotransmission which depends on the production of acetylcholine at synapses.
cholinergic receptors
receptor sites on effector organs or at nerve synapses that are stimulated by acetylcholine released by the nerve terminal. There are two types: muscarinic receptors, present primarily on autonomic effector cells, and nicotinic receptors, present primarily on autonomic ganglion cells and on the motor end plates of skeletal muscle.