The cholinergic agent
physostigmine is capable of reversing the central nervous system effects of anticholinergics, such as scopolamine and tricyclic antidepressants.
The cholinergic agent
galantamine improved verbal fluency and reduced cognitive errors of commission when added to antipsychotic therapy in 24 adults with schizophrenia, Dr.
This maintains excitable cells in a depolarized state, in which they behave like cholinergic agents
and cause dose-dependent hypotension, bradycardia and respiratory-rate depression (3).
24) Cholinergic agents
are also being developed for PET imaging and may provide additional evidence for the cholinergic hypothesis of AD, as well as provide insight into the functional mechanisms of novel drug therapies directed to the cholinergic system.
The drugs in question are known as cholinergic agents
, which interact with the brain to counter nicotine addiction.
A review of cholinergic agents
in the treatment of neurobehavioral deficits following traumatic brain injury, J Neuropsychiatry Clin Neurosci.
Modafinil and cholinergic agents
remain untested in the adolescent population.
Therefore, to elucidate potential sites of action of cholinergic agents
which are known to inhibit myopia, it is essential to investigate the regulation of the cholinergic system in the retina, choroid and sclera during normal and myopic eye development.
PHARMACOLOGICAL STUDIES EXAMINING THE EFFECTS OF CHOLINERGIC AGENTS ON THE EMBRYONIC CHICK PANCREAS.
Source: Decision Resources, March 2000 Note: Table made from bar graph Feature Comparison: Cholinergic Agents
Dose Drug MoA Binding Escalation Dosing Galantamine AChEI Competitive, reversible 4-week steps BID nAChR Allosteric modulation Donepezil AChEI Noncompetitive, 4-6-week steps QD reversible Rivastigmine AChEI Noncompetitive, 2-week steps BID reversible Prevalence of Symptoms of Psychosis and Agitation in Dementia Neuropsychiatric Dementia No Dementia Inventory Item (n = 329) (n = 673) Apathy 27.
ANALYSIS OF THE EFFECTS OF SELECTIVE CHOLINERGIC AGENTS ON DIGESTIVE ENZYME RELEASE FROM AN EMBRYONIC CHICK ORGAN CULTURE SYSTEM.
Nothing has been conclusively shown to be effective, although SSRIs, atypical antipsychotics, cholinergic agents
, and glutamatergic agents have shown some promise, according to Dr.