choline acetyltransferase

choline acetyltransferase /cho·line ac·e·tyl·trans·fer·ase/ (ko´lēn as″ĕ-tēl-trans´fer-ās) an enzyme catalyzing the synthesis of acetylcholine; it is a marker for cholinergic neurons.

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choline acetyltransferase

n.

An enzyme, present at the presynaptic ends of axons, that catalyzes the transfer of the acetyl group of acetyl CoA to choline, forming acetylcholine.

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choline [ko´lēn]

an amine that occurs in phosphatidylcholine and acetylcholine, and is an important methyl donor in intermediary metabolism. Choline is a lipotropic agent, a substance that decreases liver fat content by increasing phospholipid turnover. It was formerly considered to be a B vitamin and is now classified as a pseudovitamin, although it is still sometimes classified as part of the vitamin B complex. Vitamin B₁₂ and folacin are involved in the synthesis of choline.

choline acetylase (choline acetyltransferase) an enzyme that brings about the synthesis of acetylcholine.

choline magnesium trisalicylate see under trisalicylate.

choline salicylate see salicylate.

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choline acetyltransferase

Choline acetylase An enzyme which controls acetylcholine production in synapses of the autonomic nervous system, muscle, and SNS, which may be depleted in Alzheimer's disease