cholic acid


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Related to cholic acid: cholesterol

cholic acid

 [ko´lik, kol´ik]
one of the primary bile acids, usually found conjugated with glycine or taurine; it facilitates fat absorption and cholesterol excretion.

cho·lic ac·id

(kō'lik as'id),
A family of steroids comprising the bile acids (or salts), generally in conjugated form (for example, glycocholic and taurocholic acids). Chemically, cholic acids are cholan-24-oic (cholanic) acids (the terminal C24 of cholane becoming a -COOH group); biologically, cholic acids are derived from cholesterol (a cholestane derivative) and display varying degrees of oxidation (OH groups) and orientation at positions 3, 7, and 12. It is these oxidations and orientations that distinguish the several cholic acid; for example, cholic acid is 3α,7α,12α-trihydroxy-5β-cholan-24-oic acid, and deoxycholic acid is 3α,12α-dihydroxy-5β-cholanic acid. Cholic acid is a naturally occurring detergent in mammals that aids in the digestion of fats.

cholic acid

/cho·lic ac·id/ (kol´ik) one of the primary bile acids in humans, usually occurring conjugated with glycine or taurine; it facilitates fat absorption and cholesterol excretion.

cholic acid

(kō′lĭk)
n.
An abundant crystalline bile acid, C24H40O5, derived from cholesterol.

cholic acid

a bile acid synthesized in the liver from cholesterol. Cholan-24-oic acid is stored in the liver bound to coenzyme A and converted to glycine and taurine bile salts before secretion into bile.

cho·lic ac·id

(kō'lik as'id)
A family of steroids comprising the bile acids (or salts), generally in conjugated form (e.g., glycocholic and taurocholic acids); cholic acids are derived from cholesterol.

cholic acid

a crystalline BILE acid.

cholic acid

a major bile acid formed in the liver from cholesterol that plays, with other bile acids, an important role in digestion.
References in periodicals archive ?
Dilution protocol of bile acids in Lowenstein-Jensen medium Lowenstein-Jensen medium with bile acid additives Lithocolic acid Cholic acid (mg/ml) (mg/ml) Dilution 1 2 32 Dilution 2 1 16 Dilution 3 0.
The first molecule, cholic acid, influences the production and survival of neurons in what is known as the 'red nucleus', which is important for incoming signals from other parts of the brain".
5% cholic acid and 1% cholesterol) for 3 weeks resulted in an increase of total cholesterol (Minhajuddin et al.
M2 EQUITYBITES-January 13, 2015-Retrophin acquires exclusive right to purchase cholic acid from Asklepion Pharmaceuticals
Biopharmaceutical company Retrophin (NasdaqGM:RTRX) reported on Monday a definitive agreement to acquire the exclusive worldwide rights, titles and ownership of cholic acid for the treatment of bile acid synthesis defects.
As part of an agreement, Retrophin has acquired the exclusive rights to purchase cholic acid from Asklepion.
M2 PHARMA-January 13, 2015-Retrophin acquires exclusive right to purchase cholic acid from Asklepion Pharmaceuticals
The farnesoid X receptor (FXR) is a receptor for bile acids such as chenodeoxycholic acid (CDCA), deoxycholic acid, cholic acid, and their conjugates.
5% cholic acid increased, as compared with those of rats fed a normal diet.
5% cholic acid diet, together with Coptidis Rhizoma extract at an oral dose of 50 or 100 mg/kg body wt.