cholic acid


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Related to cholic acid: cholesterol

cholic acid

 [ko´lik, kol´ik]
one of the primary bile acids, usually found conjugated with glycine or taurine; it facilitates fat absorption and cholesterol excretion.

cho·lic ac·id

(kō'lik as'id),
A family of steroids comprising the bile acids (or salts), generally in conjugated form (for example, glycocholic and taurocholic acids). Chemically, cholic acids are cholan-24-oic (cholanic) acids (the terminal C24 of cholane becoming a -COOH group); biologically, cholic acids are derived from cholesterol (a cholestane derivative) and display varying degrees of oxidation (OH groups) and orientation at positions 3, 7, and 12. It is these oxidations and orientations that distinguish the several cholic acid; for example, cholic acid is 3α,7α,12α-trihydroxy-5β-cholan-24-oic acid, and deoxycholic acid is 3α,12α-dihydroxy-5β-cholanic acid. Cholic acid is a naturally occurring detergent in mammals that aids in the digestion of fats.

cholic acid

/cho·lic ac·id/ (kol´ik) one of the primary bile acids in humans, usually occurring conjugated with glycine or taurine; it facilitates fat absorption and cholesterol excretion.

cholic acid

(kō′lĭk)
n.
An abundant crystalline bile acid, C24H40O5, derived from cholesterol.

cholic acid

a bile acid synthesized in the liver from cholesterol. Cholan-24-oic acid is stored in the liver bound to coenzyme A and converted to glycine and taurine bile salts before secretion into bile.

cho·lic ac·id

(kō'lik as'id)
A family of steroids comprising the bile acids (or salts), generally in conjugated form (e.g., glycocholic and taurocholic acids); cholic acids are derived from cholesterol.

cholic acid

a crystalline BILE acid.

cholic acid

a major bile acid formed in the liver from cholesterol that plays, with other bile acids, an important role in digestion.
References in periodicals archive ?
Delivery of this report on global and Chinese cholic acid market, 2009-2019 will take 2-3 working days once order is placed.
The first molecule, cholic acid, influences the production and survival of neurons in what is known as the "red nucleus", which is important for incoming signals from other parts of the brain.
These included a deoxycholic acid culture at 8 mg/ml and 3 cholic acid cultures with the following concentrations: 16 mg/ml, 8 mg/ml and 4 mg/ml.
demonstrated that feeding rats with cholic acid and cholesterol down-regulates the transcription of CYP7A1 through simulation of the nuclear farnesoid X receptors (Xu et al.
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Laboratoires CTRS (Cell Therapies Research & Services) ( CTRS ) has developed the medicinal product Orphacol, which contains cholic acid as an active substance.
Professor William J Griffiths said: "These two molecules are named cholic acid and 24S, 25-epoxycholesterol, a bile acid and a close relative of cholesterol, respectively.
62mmol/l) a 1% cholesterol-enriched diet (casein, 200 (95% purity) (Prolabo, Paris, France) combined with Isio 4 oil, 50; sucrose, 40; cornstarch, 585; cellulose, 50; vitamins, 20; minerals 40; cholesterol, 10; cholic acid 5 (Merck, Darmstadt, Germany) (to facilitate cholesterol absorption) for 15 days.
Unlike Cyp7a1 this gene does not appear to be downregulated by cholic acid through the farnesoid X bile acid receptor (Sinal et al.