cholestyramine resin

resin /res·in/ (rez´in)

1. a solid or semisolid organic substance exuded by plants or by insects feeding on plants, or produced synthetically; they are insoluble in water but mostly soluble in alcohol or ether.

2. a compound made by condensation or polymerization of low-molecular-weight organic compounds.res´inous

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acrylic resins  a class of thermoplastic resins produced by polymerization of acrylic or methacrylic acid or their derivatives; used in the fabrication of medical prostheses and dental restorations and appliances.

anion exchange resin  see ion exchange r.

cation exchange resin  see ion exchange r.

cholestyramine resin  a synthetic, strongly basic anion exchange resin in the chloride form which chelates bile acids in the intestine, thus preventing their reabsorption; used as an adjunctive therapy to diet in management of certain hypercholesterolemias and in the symptomatic relief of pruritus associated with bile stasis.

composite resin  a synthetic resin, usually acrylic based, to which a high percentage of inert filler has been added, e.g., coated glass or silica; used chiefly in dental restorations.

epoxy resin  a heat-set resin with toughness, adhesibility, chemical resistance, dielectric properties, and dimensional stability; several modified types are used as denture base material.

ion exchange resin  a high-molecular-weight insoluble polymer of simple organic compounds capable of exchanging its attached ions for other ions in the surrounding medium; classified as (a) cation or anion exchange r's, depending on which ions the resin exchanges; and (b) carboxylic, sulfonic, etc., depending on the nature of the active groups.

podophyllum resin  podophyllin; a mixture of resins from podophyllum, used as a topical caustic in the treatment of certain papillomas, condylomata acuminata, keratoses, and other epitheliomas.

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cholestyramine resin,

an ion-exchange resin and antihyperlipemic agent.

indications It is prescribed for oral administration to increase bile acid excretion in the stool, for the treatment of hyperlipoproteinemia, and for pruritus resulting from partial biliary obstruction.

contraindications Complete biliary obstruction or known hypersensitivity to this drug prohibits its use.

adverse effects Among the more serious adverse reactions are fecal impaction, GI disturbances, and depletion of vitamins A, D, and K. Constipation is common. It interferes with the absorption of many other drugs, so other medicines should be given 1 hr before or 4-6 hr after cholestyramine.

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resin

1. a solid or semisolid, amorphous organic substance of vegetable origin or produced synthetically. True resins are insoluble in water, but are readily dissolved in alcohol, ether and volatile oils.

2. rosin.

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acrylic r's

products of the polymerization of acrylic or methacrylic acid or their derivatives and used in the fabrication of surgical prostheses and equipment.

anion-exchange resin

see ion-exchange resin.

cation-exchange resin

see ion-exchange resin.

cholestyramine resin

a synthetic, strongly basic anion-exchange resin in the chloride form which chelates bile salts in the intestine, thus preventing their reabsorption.

composite resin

usually a mixture of organic matrix and inorganic filler, used in restorative dentistry.

ipomoea resin, jalap resin, scammony resin

severe cathartics and irritants; little used because of their disastrous effects.