granuloma (redirected from cholesterol granuloma)

granuloma /gran·u·lo·ma/ (gran″u-lo´mah) pl. granulomas, granulo´mata   an imprecise term for (1) any small nodular delimited aggregation of mononuclear inflammatory cells, or (2) such a collection of modified macrophages resembling epithelial cells, usually surrounded by a rim of lymphocytes.

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actinic granuloma  a round lesion with a raised border seen on skin chronically exposed to sunlight.

granuloma annula´re  a benign, self-limited disease consisting of round granulomas of the dermis in groups, with papules or nodules, mainly seen in young girls.

apical granuloma  modified granulation tissue containing elements of chronic inflammation, located adjacent to the root apex of a tooth with infected, necrotic pulp.

coccidioidal granuloma  secondary coccidioidomycosis.

eosinophilic granuloma 

1. Langerhans cell histiocytosis.

2. a disorder similar to eosinophilic gastroenteritis, with localized nodular or pedunculated lesions of the submucosa and muscle walls, especially of the pyloric area of the stomach, caused by infiltration of eosinophils, but without peripheral eosinophilia or allergic symptoms.

3. anisakiasis.

granuloma fissura´tum  a firm, red, fissured, fibrotic granuloma of the gum and buccal mucosa of an edentulous alveolar ridge between the ridge and cheek; caused by an ill-fitting denture.

infectious granuloma  one due to a specific microorganism, as tubercle bacilli.

granuloma inguina´le  a granulomatous venereal disease, usually seen in dark-skinned people, marked by purulent ulceration of the external genitals, caused by Calymmatobacterium granulomatis.

lethal midline granuloma  a rare lethal necrotizing granuloma that destroys the midface; it is nearly always preceded by longstanding nonspecific inflammation of the nose or nasal sinuses, with purulent, often bloody discharge.

lipoid granuloma  xanthoma.

lipophagic granuloma  granuloma with loss of subcutaneous fat.

midline granuloma  lethal midline g.

paracoccidioidal granuloma  paracoccidioidomycosis.

peripheral giant cell reparative granuloma  giant cell epulis.

pyogenic granuloma  a benign, solitary nodule resembling granulation tissue, found anywhere but often in the mouth, usually at the site of trauma as a tissue response to nonspecific infection.

reticulohistiocytic granuloma  a solitary reticulohistiocytoma that is not associated with systemic involvement.

sarcoid granuloma  the granuloma seen with sarcoidosis.

swimming pool granuloma  one that complicates injuries sustained in swimming pools, attributed to Mycobacterium balnei, often healing spontaneously over time.

trichophytic granuloma  tinea corporis, usually on the lower legs, due to Trichophyton infecting hairs at the site, with raised, circumscribed, boggy granulomas, scattered or in chains; lesions are slowly absorbed, or undergo necrosis, leaving scars.

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gran·u·lo·ma (grny-lm)

n. pl. gran·u·lo·mas or gran·u·lo·ma·ta (-m-t)

A mass of inflamed granulation tissue, usually associated with ulcerated infections.

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granu·loma·tous (-m-ts) adj.

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Granuloma

A collection of inflammatory cells forming a microscopic lesion, many of which are scattered throughout the lung tissue in patients who have had numerous acute episodes of HP.

Mentioned in: Granuloma Inguinale, Hypersensitivity Pneumonitis, Prostatitis, Roundworm Infections, Sarcoidosis

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granuloma

[gran′yoo͡lō′mə] pl. granulomas, granulomata

Etymology: L, granulum + Gk, oma, tumor

a chronic inflammatory lesion most commonly caused by histoplasmosis, a fungal infection. It is characterized by an accumulation of macrophages; epithelioid macrophages, with or without lymphocytes; and giant cells into a discrete granule. Granulomas most often occur in the lungs. They may resolve spontaneously, remain static, become gangrenous, spread, or act as a focus of infection. Treatment depends on the cause and probable course of the particular granuloma.

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granuloma (gran·y·lōˑ·m),

n persistent, inflamed lesion notable for its abundance of macrophages.

Granuloma.

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granuloma (gran´ūlō´m),

n a localized mass of granulation tissue characterized by an accumulation of macrophages, epithelioid macrophages, with or without lymphocytes, and giant cells into a discrete mass.

Granuloma.

granuloma, central giant cell,

n a painless, benign, expansile lesion on bone, usually on the anterior mandible, less frequently crossing the midline of the mandible. Usually contain a number of multinucleated giant cells.

granuloma, chronic,

n (chronic apical periodontitis) a chronic inflammatory tissue surrounding the apical foramina as a result of irritation from within the root canal system.

granuloma, dental,

n a mass of granulation tissue surrounded by a fibrous capsule attached at the apex of a pulp-involved tooth. It produces a radiolucency that is fairly well demarcated.

granuloma, eosinophilic

n a granulomatous inflammatory disease of unknown etiology, usually monofocal in bone but sometimes affecting soft tissues. Sheets of histiocytes and masses of eosinophils characterize the lesion histologically. See also disease, Langerhans cell.

granuloma, giant cell reparative,

n an inflammatory lesion located near the gingival margin. It takes the shape of a mushroom, has a smooth, glossy surface, bleeds easily, and tends to reoccur after removal. It generally occurs in the third trimester of pregnancy. See also granuloma, pyogenic and granuloma, central giant cell.

granuloma inguinale

n a sexually transmitted disease characterized by ulcers of the skin and subcutaneous tissues of the groin and genitalia. It is caused by infection with
C. granulomatis, a small, gram-negative, rod-shaped bacillus.

granuloma, pyogenic,

n a tumorlike mass of granulation tissue produced in response to minor trauma in some individuals. It is not suppuration producing, as the name suggests, but is highly vascular and bleeds readily. They are histologically identical to pregnancy granulomas, but they may be found in either gender in any location, and may occur at any age. Some prefer the term
lobular capillary hemangioma to describe a pyogenic granuloma, as it more accurately describes the histologic findings.

granuloma, reticuloendothelial

n See disease, lipoid storage.

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granuloma

a tumor-like mass or nodule of granulation tissue, with actively growing fibroblasts and capillary buds, consisting of a collection of modified macrophages resembling epithelial cells, surrounded by a rim of mononuclear cells, chiefly lymphocytes, and sometimes a center of giant multinucleate cells; it is due to a chronic inflammatory process associated with infectious disease or invasion by a foreign body.

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acropruritic granuloma

see acral lick dermatitis.

apical granuloma

modified granulation tissue containing elements of chronic inflammation located adjacent to the root apex of a tooth with infected necrotic pulp.

canine eosinophilic granuloma

see eosinophilic granuloma.

cholesterol granuloma

see cholesteatoma.

coccidioidal granuloma

the secondary, progressive, chronic (granulomatous) stage of coccidioidomycosis.

dental granuloma

one usually surrounded by a fibrous sac continuous with the periodontal ligament and attached to the root apex of a tooth.

enzootic nasal granuloma

see enzootic nasal granuloma.

equine dermal granuloma

see swamp cancer.

feline lick granuloma

see feline eosinophilic granuloma complex.

granuloma fissuratum

a firm, whitish, fissured, fibrotic granuloma of the gum and buccal mucosa, occurring on an edentulous alveolar ridge and between the ridge and the cheek.

foreign body granuloma

a localized histiocytic reaction to a foreign body in the tissue.

idiopathic sterile g's

occur in dogs and cats; the lesions are painless and may become ulcerated and secondarily infected. An immune-mediated cause is suspected and the lesions often respond to treatment with corticosteroids or other immunomodulating drugs. Sometimes lesions regress spontaneously.

infectious granuloma

infection by one of the systemic mycotic fungal agents which result in a granulomatous lesion in the skin.

intestinal eosinophilic granuloma

see angiostrongyluscostaricensis.

linear granuloma

well-delineated, elevated plaques with an eroded surface that occur in a linear pattern, usually on the caudal aspect of the hindleg(s) of cats. Pruritus is variable. Similar lesions may also occur in the oral cavity and on the lips. See also feline eosinophilic granuloma complex.

lipoid granuloma

a granuloma containing lipoid cells; xanthoma.

lipophagic granuloma

a granuloma attended by the loss of subcutaneous fat.

mycotic granuloma

see swamp cancer.

palisading granuloma

one characterized by the arrangement of histiocytes surrounding a focus of fibrin, foreign material, degenerating collagen.

paracoccidioidal granuloma

paracoccidioidomycosis.

peripheral giant cell reparative granuloma

a pedunculated or sessile lesion of the gingivae or alveolar ridge, apparently arising from the periodontium or mucoperiosteum, and usually due to trauma. It is uncommon in humans and animals. Called also reparative granuloma of the jaw.

pressure point granuloma

see pressure points.

pyogenic granuloma

a benign, solitary, nodule resembling granulation tissue, found anywhere on the body, commonly intraorally, usually at the site of trauma as a response of the tissues to a nonspecific infection.

reparative granuloma of the jaw

see peripheral giant cell reparative granuloma (above).

sperm granuloma

granuloma of the epididymis caused by leakage of spermatozoa from the efferent tubules or the epididymis into surrounding tissue. May be due to trauma, infection or to congenital defects in the duct system.

staphylococcal granuloma

a large mass containing small abscesses, found in the wall of the uterus of the sow. See also botryomycosis.

telangiectatic granuloma

a form characterized by numerous dilated blood vessels.

tuberculous granuloma

the lesion of tuberculosis and the prototype of granulomatous inflammation. It is composed of histiocytes and epithelioid cells surrounded by giant cells of the Langhans type, lymphocytes and fibroblasts. Bacteria are found in the cytoplasm of the epithelioid and giant cells.

ulcerative granuloma of swine

see ulcerative granuloma of swine.

venereal granuloma

see canine transmissible venereal tumor.

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granuloma

Growth appearing like a nodule, consisting essentially of granulation tissue and occurring as a result of localized inflammation. It can appear on the conjunctiva, the iris, the lacrimal gland, or the orbit.

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granuloma

1. A nodular aggregate of epithelioid histiocytes or macrophages surrounded by lymphocytes, often accompanied by multinucleated epithelioid cells, and scattered CD4 T cells in the center, which function in antigen recognition, surrounded by a rim of collagen, rare CD8 T cells and proliferating fibroblasts DiffDx Chronic infection, sarcoidosis, and drug toxicity; if necrotic, TB is suspected; eosinophils favors allergy 2. A nonspecific term which may be used by nonpathologists for any rounded mass or bump. See Central giant cell granuloma, Ceroid granuloma, Doughnut granuloma, Eosinophilic granuloma, Epithelioid granuloma, Fish tank granuloma, Giant cell granuloma, Giant cell reparative granuloma, Juvenile xanthogranuloma, Lethal midline granuloma, Lymphogranuloma venereum, Midline granuloma, Naked granuloma, Peripheral giant cell granuloma, Pregnancy granuloma, Pulse granuloma, Pyogenic granuloma, Swimming pool granuloma.