cholesterol granuloma

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cholesterol granuloma

granuloma with prominent clefts of cholesterol surrounded by foreign-body giant cells found in chronic otitis media and sinusitis.

cho·les·ter·ol gran·u·lo·ma

(kŏ-les'tĕr-ol gran'yū-lō'mă)
Granuloma with prominent clefts of cholesterol surrounded by foreign-body giant cells found in chronic otitis media and sinusitis.


a tumor-like mass or nodule of granulation tissue, with actively growing fibroblasts and capillary buds, consisting of a collection of modified macrophages resembling epithelial cells, surrounded by a rim of mononuclear cells, chiefly lymphocytes, and sometimes a center of giant multinucleate cells; it is due to a chronic inflammatory process associated with infectious disease or invasion by a foreign body.

acropruritic granuloma
see acral lick dermatitis.
apical granuloma
modified granulation tissue containing elements of chronic inflammation located adjacent to the root apex of a tooth with infected necrotic pulp.
canine eosinophilic granuloma
see eosinophilic granuloma.
cholesterol granuloma
coccidioidal granuloma
the secondary, progressive, chronic (granulomatous) stage of coccidioidomycosis.
dental granuloma
one usually surrounded by a fibrous sac continuous with the periodontal ligament and attached to the root apex of a tooth.
enzootic nasal granuloma
see enzootic nasal granuloma.
equine dermal granuloma
feline lick granuloma
see feline eosinophilic granuloma complex.
granuloma fissuratum
a firm, whitish, fissured, fibrotic granuloma of the gum and buccal mucosa, occurring on an edentulous alveolar ridge and between the ridge and the cheek.
foreign body granuloma
a localized histiocytic reaction to a foreign body in the tissue.
idiopathic sterile g's
occur in dogs and cats; the lesions are painless and may become ulcerated and secondarily infected. An immune-mediated cause is suspected and the lesions often respond to treatment with corticosteroids or other immunomodulating drugs. Sometimes lesions regress spontaneously.
infectious granuloma
infection by one of the systemic mycotic fungal agents which result in a granulomatous lesion in the skin.
intestinal eosinophilic granuloma
see angiostrongyluscostaricensis.
linear granuloma
well-delineated, elevated plaques with an eroded surface that occur in a linear pattern, usually on the caudal aspect of the hindleg(s) of cats. Pruritus is variable. Similar lesions may also occur in the oral cavity and on the lips. See also feline eosinophilic granuloma complex.
lipoid granuloma
a granuloma containing lipoid cells; xanthoma.
lipophagic granuloma
a granuloma attended by the loss of subcutaneous fat.
mycotic granuloma
palisading granuloma
one characterized by the arrangement of histiocytes surrounding a focus of fibrin, foreign material, degenerating collagen.
paracoccidioidal granuloma
peripheral giant cell reparative granuloma
a pedunculated or sessile lesion of the gingivae or alveolar ridge, apparently arising from the periodontium or mucoperiosteum, and usually due to trauma. It is uncommon in humans and animals. Called also reparative granuloma of the jaw.
pressure point granuloma
see pressure points.
pyogenic granuloma
a benign, solitary, nodule resembling granulation tissue, found anywhere on the body, commonly intraorally, usually at the site of trauma as a response of the tissues to a nonspecific infection.
reparative granuloma of the jaw
see peripheral giant cell reparative granuloma (above).
sperm granuloma
granuloma of the epididymis caused by leakage of spermatozoa from the efferent tubules or the epididymis into surrounding tissue. May be due to trauma, infection or to congenital defects in the duct system.
staphylococcal granuloma
a large mass containing small abscesses, found in the wall of the uterus of the sow. See also botryomycosis.
telangiectatic granuloma
a form characterized by numerous dilated blood vessels.
tuberculous granuloma
the lesion of tuberculosis and the prototype of granulomatous inflammation. It is composed of histiocytes and epithelioid cells surrounded by giant cells of the Langhans type, lymphocytes and fibroblasts. Bacteria are found in the cytoplasm of the epithelioid and giant cells.
ulcerative granuloma of swine
see ulcerative granuloma of swine.
venereal granuloma
see canine transmissible venereal tumor.
References in periodicals archive ?
Our search of the English literature revealed that the first case of an epididymal cholesterol granuloma was reported by Nistal and colleagues.
Endoscopic sinus surgery in cases of cholesterol granuloma of the maxillary sinus.
Computed tomography (CT) and magnetic resonance imaging (MRI) were done on both patients and revealed cholesterol granulomas of the left petrous apex (Fig.
Sinonasal cholesterol granuloma usually presents in patients with a history of rhinitis or sinus disease (or sinus surgery) with facial pain, headache, nasal obstruction, and nasal discharge.
In conclusion, patients with a large petrous apex cholesterol granuloma may experience extensive bone erosion involving the jugular foramen, carotid canal, and internal auditory canal.
MRI had revealed a heterogeneous, hyperintense lesion within the right petrous apex on both T1- and T2-weighted imaging, consistent with a cholesterol granuloma.
According to Sade, what we consider to be a case of idiopathic hemotympanum is actually a case of granular mastoiditis in which a cholesterol granuloma dominates the pathologic picture; it appears in the tympanic cavity and imparts a steel-blue color to the drum.
Final pathology was consistent with a cholesterol granuloma.
The factors necessary for the development of a cholesterol granuloma are hemorrhage, interference with clearance or drainage, and obstruction of air exchange or ventilation.
A cholesterol granuloma of the tip of the petrous bone is a smoothly expanding mass that contains cholesterol crystals, hemosiderin-laden macrophages, fibrous tissue, chronic inflammatory cells, and blood vessels.
Xanthogranulomas, known as cholesterol granulomas, are characterized by both granuloma and xanthoma.

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