cholesterol embolization syndrome

cholesterol embolization syndrome

Atheroembolic renal disease Vascular disease A condition affecting ± 4/10,000, more common in ♂ ≥ age 60, in which showers of cholesterol and debris from atherosclerotic plaques embolize to renal arterioles, blocking blood flow, resulting in renal infarction and possibly renal failure Risk factors ASHD, DM, HTN, smoking, obesity, hyperlipidemia. See Atherosclerotic heart disease.

cholesterol embolization syndrome

The systemic consequences that result from the splintering of cholesterol-containing plaques from the aorta; when this occurs fragments of cholesterol crystals may travel to and obstruct blood vessels throughout the body. The renal, mesenteric, and femoral arteries are most often affected; involvement of the cerebral vessels is unusual. This condition may arise after trauma to the aorta (e.g., during catheterization or cardiac surgery). It may produce renal failure, and ischemia or infarction of the bowel, toes, or skin. It may ultimately result in death in about half of all affected patients. There is no effective treatment.
References in periodicals archive ?
Abstract: Cholesterol embolization syndrome is a rare but devastating complication of thrombolysis.
Thrombolytic-induced cholesterol embolization syndrome (CES) was first recognized in 1984 by Glassock et al (1) in a patient who had acute renal failure, hypertension, and skin necrosis after receiving streptokinase for a deep vein thrombosis.
Cholesterol embolization syndrome occurs in 1%-2% of patients undergoing cardiac catheterization and often goes unrecognized, according to Dr.
In what they describe as the first prospective study of the incidence of cholesterol embolization syndrome, 1,786 consecutive patients who underwent cardiac catheterization at 11 hospitals were evaluated for both obvious and occult signs.