intrahepatic cholestasis of pregnancy

(redirected from cholestasis of pregnancy)

intrahepatic cholestasis of pregnancy

intrahepatic cholestasis with centrilobular bile staining without inflammatory cells or proliferation of mesenchymal cells; clinically characterized by pruritus and icterus; of unknown cause but associated with high estrogen levels.

intrahepatic cholestasis of pregnancy

a type of intrahepatic cholestasis sometimes seen during the third trimester of pregnancy, characterized by severe itching, hepatomegaly, and sometimes jaundice. It clears up after delivery. The cause is unknown, but because it occurs far more in certain ethnic groups than in others, there may be a genetic link.

in·tra·he·pat·ic cho·le·sta·sis of preg·nan·cy

(in'tră-hĕ-pat'ik kō'lē-stā'sis preg'năn-sē)
Intrahepatic cholestasis with centrilobular bile staining without inflammatory cells or proliferation of mesenchymal cells; clinically characterized by pruritus and/or icterus; of unknown cause but associated with high estrogen levels.
Synonym(s): cholestasis of pregnancy, recurrent jaundice of pregnancy.

intrahepatic cholestasis of pregnancy

Abbreviation: ICP
A complication of approx. 1% of pregnancies in which elevated levels of pregnancy hormones cause obstruction to bile flow within the liver. Levels of bilirubin rise in the maternal circulation during the second and third trimesters of pregnancy, causing itching, bile staining of urine, and a lighter stool color than normal. ICP increases the risk of preterm delivery of the fetus and of bleeding disorders and loss of life of the fetus. Synonym: obstetric cholestasis
See also: cholestasis
References in periodicals archive ?
Her daughter Wren Ivy - who she had with co-star Jack Ashton - was born three weeks prematurely in September due to a condition called Intrahepatic cholestasis of pregnancy, in which there is a build-up of bile acids in the liver
However, no significant difference was noted in the rate of intrahepatic cholestasis of pregnancy between the study group and control group ( P > 0.
Liver diseases that occur during pregnancy include hyperemesis gravidarum (HG), intra-hepatic cholestasis of pregnancy, acute fatty liver of pregnancy and the HELLP syndrome (1, 2).
Leevy described 4 Puerto Rican sisters who had prolonged recurrent cholestasis of pregnancy, accompanied by pruritus with every pregnancy (8).
Few studies have reported highly significant incidence of intrahepatic cholestasis of pregnancy in Hepatitis C positive pregnant women.
Objective: To evaluate the associations between adverse perinatal outcomes and serum transaminase levels at the time of diagnosis in patients with intrahepatic cholestasis of pregnancy.
Intrahepatic cholestasis of pregnancy (ICP), formerly known as pruritus gravidarum, is due to a defect in the excretion of bile salts, causing the excess to deposit on the skin.
Keywords: Atopic eruptions, intrahepatic cholestasis of pregnancy, polymorphic eruptions, pemphigoid gestationis, pregnancy-induced dermatoses.
He included Intrahepatic Cholestasis of Pregnancy (ICP) in his classification for dermatoses where secondary skin lesions due to scratching are produced.
Objective: To find out the frequency of intrahepatic cholestasis of pregnancy and its identification parameters.
maternal request, decrease fetal movements and cholestasis of pregnancy.
The latter include progressive familial intrahepatic cholestasis (PFIC), benign recurrent intrahepatic cholestasis (BRIC), intrahepatic cholestasis of pregnancy (ICP), and DILI.