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An arrest in the flow of bile; cholestasia due to obstruction of bile ducts is accompanied by formation of plugs of inspissated bile in the small ducts, canaliculi in the liver, and elevation of serum direct bilirubin and some enzymes.
Synonym(s): cholestasis
[chole- + G. stasis, a standing still]


An arrest in the flow of bile.
[chole- + G. stasis, a standing still]


, cholestasia (ko?le-sta'sis) (ko?le-sta'zh(e-)a) [ chole- + stasis]
Arrest of the flow of bile. This may be due to intrahepatic causes, obstruction of the bile duct by gallstones, or any process that blocks the bile duct (e.g., cancer). cholestatic (ko?le-stat'ik), adjective

intrahepatic cholestasis of pregnancy

Abbreviation: ICP
A complication of approx. 1% of pregnancies in which elevated levels of pregnancy hormones cause obstruction to bile flow within the liver. Levels of bilirubin rise in the maternal circulation during the second and third trimesters of pregnancy, causing itching, bile staining of urine, and a lighter stool color than normal. ICP increases the risk of preterm delivery of the fetus and of bleeding disorders and loss of life of the fetus. Synonym: obstetric cholestasis

obstetric cholestasis

Intrahepatic cholestasis of pregnancy.

progressive familial intrahepatic cholestasis

Byler disease.