cholic acid(redirected from cholanic acid)
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Related to cholanic acid: cholic acid, Chenodeoxycholic acid
cholic acid[ko´lik, kol´ik]
cho·lic ac·id(kō'lik as'id),
A family of steroids comprising the bile acids (or salts), generally in conjugated form (for example, glycocholic and taurocholic acids). Chemically, cholic acids are cholan-24-oic (cholanic) acids (the terminal C24 of cholane becoming a -COOH group); biologically, cholic acids are derived from cholesterol (a cholestane derivative) and display varying degrees of oxidation (OH groups) and orientation at positions 3, 7, and 12. It is these oxidations and orientations that distinguish the several cholic acid; for example, cholic acid is 3α,7α,12α-trihydroxy-5β-cholan-24-oic acid, and deoxycholic acid is 3α,12α-dihydroxy-5β-cholanic acid. Cholic acid is a naturally occurring detergent in mammals that aids in the digestion of fats.
cholic acid/cho·lic ac·id/ (kol´ik) one of the primary bile acids in humans, usually occurring conjugated with glycine or taurine; it facilitates fat absorption and cholesterol excretion.
An abundant crystalline bile acid, C24H40O5, derived from cholesterol.
a bile acid synthesized in the liver from cholesterol. Cholan-24-oic acid is stored in the liver bound to coenzyme A and converted to glycine and taurine bile salts before secretion into bile.
cho·lic ac·id(kō'lik as'id)
A family of steroids comprising the bile acids (or salts), generally in conjugated form (e.g., glycocholic and taurocholic acids); cholic acids are derived from cholesterol.
cholic acida crystalline BILE acid.
a major bile acid formed in the liver from cholesterol that plays, with other bile acids, an important role in digestion.