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chlorpromazine |
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chlorpromazine /chlor·pro·ma·zine/ (-pro´mah-zen) a phenothiazine used in the form of the base or the hydrochloride salt as an antipsychotic, antiemetic, and presurgical sedative, and in the treatment of intractable hiccups, acute intermittent porphyria, tetanus, the manic phase of bipolar disorder, and severe behavioral problems in children.
chlorpromazine a phenothiazine used as an antipsychotic agent and antiemetic. It has been largely superseded in veterinary work by acetylpromazine. Its principal use was as premedication for anesthesia. |
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| Chlorpromazine has no anti-motion sickness efficacy, even though it is quite effective against chemically induced nausea. In this regard, the distribution of brevetoxins by ip toxin exposure is not likely to reflect distribution of toxin by oral exposure, as was demonstrated for chlorpromazine and imipramine (Bickel 1975). When the first modern psychiatric wonder drug, chlorpromazine (Thorazine), was introduced in France in 1950, it was as an anesthetic. |
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