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chlorproMAZINE |
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chlorpromazine /chlor·pro·ma·zine/ (-pro´mah-zēn) a phenothiazine used in the form of the base or the hydrochloride salt as an antipsychotic, antiemetic, and presurgical sedative, and in the treatment of intractable hiccups, acute intermittent porphyria, tetanus, the manic phase of bipolar disorder, and severe behavioral problems in children.
chlorproMAZINE [-prō′məzēn] a phenothiazine drug used as an antipsychotic and antiemetic. indications It is prescribed in the treatment of psychotic disorders (mania, schizophrenia), severe nausea and vomiting, and intractable hiccups. contraindications Parkinson's disease, concurrent administration of central nervous system depressants, liver or renal dysfunction, severe hypotension, or known hypersensitivity to this drug or to other phenothiazine medication prohibits its use. adverse effects Among the more serious adverse effects are hypotension, alteration in cardiac conduction, liver toxicity, a variety of extrapyramidal reactions, blood dyscrasias, and hypersensitivity reactions. chlorpromazine a phenothiazine used as an antipsychotic agent and antiemetic. It has been largely superseded in veterinary work by acetylpromazine. Its principal use was as premedication for anesthesia. chlorpromazine Thorazine® An aliphatic phenothiazine, neuroleptic, antipsychotic, with antiadrenergic, anticholinergic, antiemetic, central antihypertensive activity How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Chlorpromazine has no anti-motion sickness efficacy, even though it is quite effective against chemically induced nausea. In this regard, the distribution of brevetoxins by ip toxin exposure is not likely to reflect distribution of toxin by oral exposure, as was demonstrated for chlorpromazine and imipramine (Bickel 1975). When the first modern psychiatric wonder drug, chlorpromazine (Thorazine), was introduced in France in 1950, it was as an anesthetic. |
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