chlormethine


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mechlorethamine

A nitrogen mustard derivative which binds to DNA, crosslinking both strands to prevent its replication.

Global village
Mechlorethamine was first developed as a chemical weapon.

Oncology
A nitrogen mustard alkylating agent used for managing lymphomas; part of MOPP.
 
Adverse effects
Nausea, vomiting, marrow suppression, skin vesiculation at injection site.

chlormethine

An alkylating drug that has been used to treat cancer. It is very toxic and causes severe vomiting. The drug is on the WHO official list.
References in periodicals archive ?
Technician Karen Beattie selected Chlormethine instead of Carmustine while he was being treated for lymphoma.
a privately held specialty pharmaceutical company, announced today that the European Medicines Agency (EMA) has granted Orphan Drug Designation to Ceptaris' investigational drug, chlormethine gel (also known as mechlorethamine gel in the US), for the treatment of Cutaneous T-Cell Lymphoma (CTCL).