chloride shift

shift (shift) a change or deviation.

---

chloride shift  the exchange of chloride (Cl−) and bicarbonate (HCO3−) between plasma and the erythrocytes occurring whenever HCO3− is generated or decomposed within the erythrocytes.

Doppler shift  the magnitude of frequency change due to the Doppler effect.

shift to the left  an increase in the percentage of neutrophils having only one or a few lobes.

shift to the right  an increase in the percentage of multilobed neutrophils.

---

chloride shift

n.

The movement of chloride ions from the plasma into red blood cells as a result of the transfer of carbon dioxide from tissues to the plasma, a process that serves to maintain blood pH.

---

chloride shift,

an exchange of chloride ions in red blood cells in peripheral tissues in response to PCO₂ of blood. The shift reverses in the lungs.

---

chloride shift (klôr´īd),

n the exchange of a chloride ion for a bicarbonate ion across the enthrocyte membrane as part of the buffering system in the blood. It accounts for the greater chloride content of venous erythrocytes than arterial erythrocytes.

---

chloride

1. a salt of hydrochloric acid; any binary compound of chlorine.

2. the principal anion in extracellular fluid and gastric juice.

Because of its domination of the anions in extracellular and intravascular fluid, it has profound importance for acid-base balance and for the regulation of osmotic pressure in these fluid compartments.

---

chloride pump

an active secretory process at a barrier membrane that facilitates the transfer of chloride ions across the membrane.

chloride shift

diffusion of chloride ions from the plasma into the erythrocytes to compensate for the loss of bicarbonate ions from the cells as a result of carbon dioxide metabolism. Called also Hamburger shift.

---

shift

a change or deviation.

---

antigenic shift

see antigenic shift.

chloride shift

see chloride shift.

shift to the left

an alteration in the distribution of leukocytes in the peripheral blood in which there is an increase in the numbers of immature neutrophils, primarily band forms but metamyelocytes or more immature cells may also be present; usually in response to an infection.

Canine blood smear showing a shift to the left with a segmented neutrophil (left) with toxic vacuolation and a metamyelocyte (right) with two Döhle bodies. By permission from Willard MD, Tvedten H, Small Animal Clinical Diagnosis by Laboratory Methods, Saunders, 2003

shift red cell

see macroreticulocyte.

shift to the right

an alteration in the distribution of leukocytes in the peripheral blood in which there is an increased number of mature neutrophils but no immature cells are present.