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chlorambucil

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chlorambucil /chlor·am·bu·cil/ (klor-am´bu-sil) an alkylating agent from the nitrogen mustard group, used as an antineoplastic.
chlor·am·bu·cil (klôr-mby-sl)
n.
An anticancer drug that is a derivitive of nitrogen mustard and is used to depress the proliferation and maturation of lymphocytes in such diseases as leukemia and Hodgkin's disease.

chlorambucil (kloram´bysil´),
n brand name: Leukeran;
drug class: antineoplastic alkylating agent;
action: inhibits enzymes that allow synthesis of amino acids in proteins;
uses: chronic lymphocytic leukemia, Hodgkin's disease, breast carcinoma, ovarian carcinoma.

chlorambucil
a nitrogen mustard derivative used as an antineoplastic agent.

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P List (a) U List (b) Epinephrine (adrenaline) P042 Chlorambucil (Leukeran) U035 Nicotine P075 Cyclophosphamide (Cytoxan, Neosar, Procytox) U058 Nitroglycerine P081 Daunomycin (Dauorubicin, Cerubidine) U059 Physostigmine P204 Diethylstilbestrol U089 Physostigmine salicylate P188 Melphalan (Alkeran) U150 Warfarin > 0.
A 74-year-old black man from Baltimore, with a history of chronic lymphocytic leukemia, chronic obstructive pulmonary disease, coronary artery disease and hypertension, was hospitalized for fatigue and anemia 4 weeks after chemotherapy with chlorambucil.
Chlorambucil--Doctors use chlorambucil to treat uveitis and meningoencephalitis.
 
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