chloral hydrate


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chloral

 [klor´al]
1. an oily liquid with a pungent, irritating odor; used in the manufacture of chloral hydrate and DDT.
chloral hydrate a sedative and hypnotic used primarily as an adjunct to anesthesia and for sedation of children before certain medical or dental procedures. It is now rarely used for management of insomnia. The Health Care Financing Administration (HCFA) guidelines for long-term care facilities discourages the use of chloral hydrate. The National Institutes of Health Consensus Conference on the Treatment of Sleep Disorders of Older People noted that hypnotic medications such as this should not be the mainstay of management of most causes of disturbed sleep.

chlo·ral hy·drate

a hypnotic and sedative; it is also used externally as a rubefacient, anesthetic, and antiseptic.

chloral hydrate

n.
A colorless crystalline compound, C2H3Cl3O2, used as a sedative and hypnotic drug and in the manufacture of DDT.

chloral hydrate

a sedative and hypnotic.
indications It is prescribed for the short-term (less than 2 wks) relief of insomnia, anxiety, or tension and as a sedative/hypnotic for diagnostic procedures.
contraindications Liver or kidney dysfunction or known hypersensitivity to this drug prohibits its use.
adverse effects Among the more serious adverse reactions are GI disturbances, skin rash, paradoxic excitement, and hypotension.

chlo·ral hy·drate

(klōrăl hīdrāt)
Hypnotic and sedative; it is also used externally as a rubefacient, anesthetic, and antiseptic.

chloral hydrate

A bitter substance used in solution as a sedative and hypnotic. The drug is on the WHO official list. A brand name is Welldorm elixir.

chlo·ral hy·drate

(klōrăl hīdrāt)
Hypnotic and sedative; also used externally as a rubefacient, anesthetic, and antiseptic.

chloral hydrate (klor´əl hī´drāt),

n brand names: Aquachloral Supprettes, Novo-chlorhydrate;
drug class: sedative-hypnotic chloral derivative, controlled substance schedule IV, schedule F;
action: produces central nervous system depression;
uses: sedation, treatment of insomnia, anesthesia adjunct.

chloral

1. an oily liquid with a pungent, irritating odor, prepared by the mutual action of alcohol and chlorine; used in the manufacture of chloral hydrate and DDT.
2. vernacular contraction of the term chloral hydrate.

chloral betaine
formed by the reaction of chloral hydrate with betaine; used as a sedative.
chloral hydrate
rarely if ever used in small animals. Widely used as a hypnotic, analgesic and anesthetic agent in large animals, especially in horses. Has many disadvantages and has been superseded by many much more satisfactory preparations. Its continued use is a matter of economics. Chloral hydrate may be administered orally but is erratic and slow-acting in its effects by this route. Intravenously the effects are immediate; injection outside the vein causes a very severe cellulitis usually terminating in an extensive slough of tissue.
Chloral hydrate is a poor analgesic and severely depressant of respiratory and vasomotor centers in the medulla.
chloral hydrate and guaiacol glyceryl ether
used as an anesthetic combination in horses; combines muscular relaxation with hypnotic effect.
chloral hydrate and magnesium sulfate
an anesthetic preparation used in horses. Combines the hypnotic effect of chloral and the neuromuscular blocking effect of magnesium.
chloral hydrate, magnesium sulfate and pentobarbital sodium
References in periodicals archive ?
Similar system of poly (vinyl butyral) film containing bromo cresol green in the presence of chloral hydrate has been examined as a radiation sensitive indicator [12].
The fist case was associated with chloral hydrate, an unpredictable medication with a long half life which is no longer widely used in our setting.
Results of medetomidine used in combination with propofol ketamine and chloral hydrate (groups B D and F) were efficient than alone.
14) Chloral hydrate in dose of 75 mg/kg was used as premedication, but it was associated with delayed onset of sedation and delayed recovery in post-operative period.
These fractures in all the species were treated by using different anesthetics like Xylazine (49 animals), chloral hydrate (4 animals), combination of Xylazine and Ketamine (37 animals) and Lignocaine hydochloride (1 animal).
Following anesthesia with intraperitoneal 10% chloral hydrate (300 mg/kg), right nephrectomy was done in these animals.
Comparison of chloral hydrate and midazolam for sedation of neonates for neuroimaging studies.
Chloral hydrate was described by Oscar Liebrich in 1869 in Berlin, where he used it as an oral premedication.
He had already become interested in eye surgery and had experimented with anesthetizing the eye with morphine, ether spray, chloral hydrate and potassium bromide, all of which were known to have effects on the nervous system.
5 mg/kg of body weight was administered as a pre-anesthetic and Chloral hydrate 1gm/10 kg of body weight (10% solution) as a general anesthesia, intravenously.
The rats were then anesthetized with chloral hydrate (350 mg/kg body wt.