chloral hydrate


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chloral

 [klor´al]
1. an oily liquid with a pungent, irritating odor; used in the manufacture of chloral hydrate and DDT.
chloral hydrate a sedative and hypnotic used primarily as an adjunct to anesthesia and for sedation of children before certain medical or dental procedures. It is now rarely used for management of insomnia. The Health Care Financing Administration (HCFA) guidelines for long-term care facilities discourages the use of chloral hydrate. The National Institutes of Health Consensus Conference on the Treatment of Sleep Disorders of Older People noted that hypnotic medications such as this should not be the mainstay of management of most causes of disturbed sleep.

chlo·ral hy·drate

a hypnotic and sedative; it is also used externally as a rubefacient, anesthetic, and antiseptic.

chloral hydrate

n.
A colorless crystalline compound, C2H3Cl3O2, used as a sedative and hypnotic drug and in the manufacture of DDT.

chloral hydrate

a sedative and hypnotic.
indications It is prescribed for the short-term (less than 2 wks) relief of insomnia, anxiety, or tension and as a sedative/hypnotic for diagnostic procedures.
contraindications Liver or kidney dysfunction or known hypersensitivity to this drug prohibits its use.
adverse effects Among the more serious adverse reactions are GI disturbances, skin rash, paradoxic excitement, and hypotension.

chlo·ral hy·drate

(klōrăl hīdrāt)
Hypnotic and sedative; it is also used externally as a rubefacient, anesthetic, and antiseptic.

chloral hydrate

A bitter substance used in solution as a sedative and hypnotic. The drug is on the WHO official list. A brand name is Welldorm elixir.

chlo·ral hy·drate

(klōrăl hīdrāt)
Hypnotic and sedative; also used externally as a rubefacient, anesthetic, and antiseptic.

chloral hydrate (klor´əl hī´drāt),

n brand names: Aquachloral Supprettes, Novo-chlorhydrate;
drug class: sedative-hypnotic chloral derivative, controlled substance schedule IV, schedule F;
action: produces central nervous system depression;
uses: sedation, treatment of insomnia, anesthesia adjunct.

chloral

1. an oily liquid with a pungent, irritating odor, prepared by the mutual action of alcohol and chlorine; used in the manufacture of chloral hydrate and DDT.
2. vernacular contraction of the term chloral hydrate.

chloral betaine
formed by the reaction of chloral hydrate with betaine; used as a sedative.
chloral hydrate
rarely if ever used in small animals. Widely used as a hypnotic, analgesic and anesthetic agent in large animals, especially in horses. Has many disadvantages and has been superseded by many much more satisfactory preparations. Its continued use is a matter of economics. Chloral hydrate may be administered orally but is erratic and slow-acting in its effects by this route. Intravenously the effects are immediate; injection outside the vein causes a very severe cellulitis usually terminating in an extensive slough of tissue.
Chloral hydrate is a poor analgesic and severely depressant of respiratory and vasomotor centers in the medulla.
chloral hydrate and guaiacol glyceryl ether
used as an anesthetic combination in horses; combines muscular relaxation with hypnotic effect.
chloral hydrate and magnesium sulfate
an anesthetic preparation used in horses. Combines the hypnotic effect of chloral and the neuromuscular blocking effect of magnesium.
chloral hydrate, magnesium sulfate and pentobarbital sodium
References in periodicals archive ?
Carcinogenicity of chloral hydrate administered in drinking water to the male F344/N rat and male B6C3F1 mouse.
Chloral hydrate is dangerous because the difference between a prescribed dose and a lethal dose is small.
An inquest, reopened at St Pancras Coroner's Court in London, heard Miss Humphreys weighed just five stone and had 20 times the recommended dose of chloral hydrate in her blood at the time of her death.
What do you think of a dentist who overdoses a patient with chloral hydrate and then deliberately lies to paramedics about it?
Toxicology studies found a massive amount of pentobarbital and chloral hydrate in her body.
KEY WORDS: alcohol dehydrogenase, aldehyde dehydrogenase, chloral hydrate, genetic variability, human hepatocytes, metabolism, risk assessment, trichloroacetate, trichloroethylene.
Most commonly, these drugs were benzodiazepines, although some patients were taking zolpidem and a few had received chloral hydrate.
The 48-year-old Pasadena dentist is charged with 14 criminal counts, including child abuse and unprofessional conduct, for allegedly giving five children overdoses of the sedative chloral hydrate while treating them.
Mr Patrick Roche, representing her father John, argued that the case should be heard in front of a jury because of the high levels of chloral hydrate Ms Humphreys had been prescribed by her doctor at a practice in Crouch End, north London.
B) Fever Blister and Cold Sore Treatment Drug Products -- Allyl Isothiocyanate, Aspirin, Bismuth Sodium Tartrate, Camphor, Capsaicin, Capsicum, Capsicum Oleoresin, Chloral Hydrate, Chlorobutanol, Cyclomethycaine Sulfate, Eucalyptus Oil, Eugenol, Glycol Salicylate, Hexylresorcinol, Histamine Dihydrochloride, Menthol, Methapyrilene Hydrochloride, Methyl Nicotinate, Methyl Salicylate, Pectin, Salicylamide, Strong Ammonia Solution, Tannic Acid, Thymol, Tripelennamine Hydrochloride, Trolamine Salicylate, Turpentine Oil, Zinc Sulfate.
The sleeping drug chloral hydrate found to be the major cause of her death was Stern's and was in a duffel bag in the Florida hotel room where she died.
Most commonly these drugs were benzodiazepines, but some patients had taken zolpidem and a few had received chloral hydrate.