chimerism


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Related to chimerism: blood chimerism

chimerism

 [ki´mer-izm]
the state of being a chimera; the presence in an individual of cells of different origin.

chi·me·rism

(kī-mēr'izm),
The state of being a chimera.

chimerism

(kī-mîr′ĭz′əm, kī′mə-rĭz′-)
n.
The condition of being a genetic chimera.

chimerism

[kimir′izəm]
a state in bone marrow transplantation in which bone marrow and host cells exist compatibly without signs of graft-versus-host rejection disease.

chimerism

the state of being a chimera; the presence in an animal of cells of different origin, e.g. XX/XY chimerism.

blood chimerism
twins that have a common circulation develop immune tolerance. Each of them is then a chimera. When the twins are of opposite sex, the female twin may be a freemartin. Sterilization of the female is brought about by the transfer of H-Y antigen to the female gonad.
References in periodicals archive ?
Despite a paucity of information for these CNDs in different ethnic populations, the potential of these CND markers for chimerism testing in diverse populations was highlighted by the in silico and in vitro frequencies being very similar (see online Supplemental Table 4).
Chimerism was not often detected prior to the introduction of SNP genotyping, as the genotypes of multiple cells would be compared only if it was suspected from an individual's phenotype.
Chimerism and microchimerism, I suggest, are the sorts of biological phenomenon that feminists might take an interest in.
While fused embryos are rare, chimerism can also result from cell swapping in utero or genetic mutation.
aGVHD is a disease often confused with drug reactions or viral infection; therefore, it is important to have a high index of suspicion and to confirm the diagnosis early with tests for donor cell chimerism.
Triple-targeted oncolytic adenoviruses featuring the cox2 promoter, E1A transcomplementation, and serotype chimerism for enhanced selectivity for ovarian cancer cells.
Second, he argued that even if his sample did prove the existence of a mixed red blood cell population, the mixed red blood cell population was not due to transfusion but rather due to chimerism, an extremely rare phenomenon where an individual's genotype can differ amongst different cells.
Her DNA blueprint was completely different to her offspring's - but it transpired she had an unusual medical condition known as chimerism, in which babies are born from the fusing of two eggs in the womb.
Morphological consequences for multi-partner chimerism in Botrylloides, a colonial urochordate.
A technique for inducing tolerance called mixed chimerism is particularly intriguing in light of the potential of a single stem cell line to generate different tissue types.
Pretreatment with high-dose iHg increases host B-cell numbers but does not alter splenic donor T-cell chimerism in chronic GVHD mice.
A: We now have pilot trials to infuse donor-derived progenitor cells from the bone marrow of the donor, called CD34 positive cells, to try to introduce chimerism and donor-specific tolerance to islets from the same donor of the bone-marrow cells.