chimera

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chimera

 [ki-me´rah]
an organism whose body contains different cell populations derived from different zygotes of the same or different species, occurring spontaneously or produced artificially.

chi·me·ra

(kī-mēr'ă, ki-),
1. In experimental embryology, the individual produced by grafting an embryonic part of one animal onto the embryo of another, either of the same or of another species.
2. An organism that has received a transplant of genetically and immunologically different tissue, such as bone marrow.
3. Dizygotic twins that exchange immunologically distinct types of erythrocytes.
4. A protein fusion in which two different proteins are linked through peptide bonds; usually genetically engineered. Chimeric antibodies may have the Fab fragment from one species fused with the Fc fragment from another.
5. Any macromolecule fusion formed by two or more macromolecules from different species or from different genes.
[L. Chimaera, G. Chimaira, mythic monster (lit. a she-goat)]

chimera

/chi·me·ra/ (ki-mir´ah)
1. an organism with different cell populations derived from different zygotes of the same or different species, occurring spontaneously or produced artificially.
2. a substance created from proteins or genes of two species, as by genetic engineering.chimer´ic

chimera

also

chimaera

(kī-mîr′ə, kĭ-)
n.
1.
a. An organism, organ, or part consisting of two or more tissues of different genetic composition, produced as a result of organ transplant, grafting, or genetic engineering.
b. A gene or protein consisting of parts from two different genes or proteins that are normally distinct, sometimes derived from two different species.
2. An individual who has received a transplant of genetically and immunologically different tissue.

chimera

[kimir′ə, kīmir′ə]
Etymology: Gk, khimaros, fire-breathing monster
an organism carrying cell populations derived from two or more different zygotes of the same or different species. Chimeras include recipients of tissue grafts from other individuals. Compare mosaic.

chimera

Any individual organism or molecule derived from 2 or more species.
 
Embryology
An organism that results when an embryonic part of one organism is grafted onto another.

Genetics
An organism with 2 or more cell lines, genotypes or karyotypes descended from at least 2 zygotes. Chimeras are very rare, only occur in twins and result from chorionic vascular anastomoses, transplantations or double fertilisations and subsequent participation of both fertilised meiotic products in one developing embryo; all hermaphrodites should be karyotyped to evaluate possible chimerism.

Molecular biology
(1) An animal formed from two different embryonic sources. In mouse genetics, targeted mutations produced in embryonic stem cells are recovered by breeding chimeric mice, resulting from the mixture of embryonic stem cells with a genetically distinct blastocyst.
(2) A clone containing genomic DNA from nonadjacent genomic segments or cDNA from two different mRNAs.

Transplantation
The term chimera was once used for a person who had received transplanted tissue—e.g., bone marrow surviving in a recipient.

chi·me·ra

(kī-mēr'ă)
1. The individual produced by grafting an embryonic part of one animal onto the embryo of another, either of the same or of another species.
2. An organism that has received a transplant of genetically and immunologically different tissue, such as bone marrow.
3. Dizygotic twins that have immunologically distinct types of erythrocytes.
4. A protein fusion in which two different proteins, usually from different species, are linked through peptide bonds; usually genetically engineered. Chimeric antibodies may have the Fab fragment from one species fused with the Fc fragment from another.
5. Any macromolecule fusion formed by two or more macromolecules from different species or from different genes.
[L. Chimaera, G. Chimaira, mythic monster (lit. a she-goat)]

chimera

An organism that contains a mixture of genetically different cells derived from more than one ZYGOTE. A chimera may, for instance, occur as a result of fertilization by more than one spermatozoon; fusion of two zygotes; an ALLOGENEIC bone marrow graft; cell exchange between dizygotic twin fetuses; or combination of portions of embryos of different species. Compare MOSAICISM. The term derives from the name of a mythical monster with a lion's head, a goat's body, and a serpent's tail.

chimera, chimaera

1. a mythological, fire-spouting monster with a lion's head, goat's body and serpent's tail.
2. an animal whose body contains different cell populations derived from different zygotes of the same or different species, occurring spontaneously or produced artificially; i.e. an individual composed of a mixture of genetically different cells.

chimera protein
see fusion protein.
References in periodicals archive ?
The set evoked the ethos of bygone days, and ingeniously allowed for intriguing entrances and exits of the chimerical creatures.
15) The district court judge dismissed the claim on summary judgment, finding that Rockwell presented contrary evidence only in a "transparent attempt to create a chimerical issue of fact.
It may be reassuring to believe there are cheap and easy things we can do as individuals to stop global warming, or that the answer is to continue chasing a chimerical global agreement on carbon cuts, as in Cancun.
The perceived task is not lighting, but rather filling sockets that used to hold incandescent lamps with something made with LEDs, and generate a need, however chimerical, to replace compact fluorescent lamps.
In her excellent study of the first two Da Ponte operas, Wye Jamison Allanbrook suggests that the chimerical style changes in Mozart's music suggest a dynamic tension between the two extremes: his Leporello, whose musical style shifts effortlessly from the most banal lower-class ditty to a near perfect mimicry of the music for the thoroughly noble Donna Anna and Don Ottavio, demonstrates how easily the servant can become a crude doppelganger of his master; by contrast, Mozart's Handelian music for Donna Elvira signifies her age and anachronistic eccentricity (Wye Jamison Allanbrook, Rhythmic Gesture in Mozart: "Le nozze di Figaro" and "Don Giovanni" [Chicago: University of Chicago Press, 1982], 201-7; 233-38).
The moot arranged by Chimerical Sciences Department was aimed at finding ways for decreasing environmental pollution, inviting suggestions for overcoming energy crisis and deciding a future course of action in this regard, the release added.
In fact, the cult has a name: Confrerie van de Roze Olifant, or Brotherhood of the Pink Elephant, a chimerical creature those afflicted with the DTs are said to behold.
Less than a week later, she apparently joined a group of 20 men who absconded 'with the chimerical idea', wrote David Collins, 'of walking to China or of finding in this country a settlement wherein they would be received and entertained without labour'.
Despite being presented as a modest single-author monograph, Coleridge, the Bible, and Religion is almost as ambitious in scope, in that it attempts to create an ordered and systematic overview of Coleridge's approach to the Bible--based structurally on the posthumously published Confessions of an Inquiring Spirit but drawing on material written and published at every stage of his life, including the chimerical Opus Maximum itself.
By 1982 most of disco's chimerical euphoria had worn off and the world had moved on; all that persisted were the commodified dreams of infinite escape, peddled by Saturday Night Fever (1977).
If Dworkin is correct then Hart's project of constructing a purely descriptive science of law that prescinds from value judgments is chimerical.
For Allawi, "the idea of pan-Islamic unity as the realistic final goal of Muslims' political action is as chimerical as a union of, say, the English-speaking world" (p.