chimeric molecule

chi·mer·ic mol·e·cule

a molecule (usually a biopolymer) containing sequences derived from two different genes; specifically, from two different species. Compare: chimera.
References in periodicals archive ?
Our study shows that in translational fusion the active domains of both Cry1Ac and Hvt remained intact and this translational fusion is highly effective chimeric molecule against agronomically important insects, which should be evaluated further for use as biopesticides or introduced in crop plants especially cotton for long lasting transgenic protection against herbivorous insects.
The similarity of these clusters to nascent junctional plaques was more easily assessed by employing a chimeric molecule containing both the E-cadherin extracellular domain and a desmosomal cadherin cytoplasmic domain.
This analysis for the chimeric molecule of CYP21P/CYP21 in CYP21 deficiency demonstrated that in this case allele dropout from the analysis of the chimeric CYP21P/CYP21 gene was attributable to the lack of specific primers for this molecule in PCR amplification.
HepaVaxx B consists of a recombinant chimeric molecule containing the elements of both a hepatitis B viral antigen and a portion of a murine antibody.
By coupling a 2-5A molecule with a specific antisense oligonucleotide, a chimeric molecule is formed that has the capacity to target specific mRNA for rapid destruction.
Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity.
Eshhar, "Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity," Proceedings of the National Academy of Sciences of the United States of America, vol.
Design, synthesis and bioactivity of catechin/ epicatechin and 2-azetidone derived chimeric molecules.
The drug discovery research collaboration is expected to focus on Yale's work on proteolysis targeting chimeric molecules (PROTACs), attempting to show that they can be turned into medicines.
So you have a molecule that essentially is genetically engineered and stitches together two different disparate kinds of activities so we have chimeric molecules.
Claude Bertrand, Ipsen's Executive Vice-President, Chief Scientific Officer said: "We are confident in the scientific rational of chimeric molecules as they can show enhanced biological activity compared to co-administered independent compounds.