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Chimeric Antibody |
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Chimeric Antibody A recombinant or genetically engineered antibody—e.g., a mouse monoclonal—which contains polypeptides or domains from a different species—e.g., humans—often introduced to reduce the antibody’s immunogenicity Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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GenScript offers extensive antibody drug services that include antigen production, hybridoma development and stabilization, antibody sequencing, chimeric antibody, antibody humanization, affinity maturation, epitope mapping, antibody and protein characterization, in vitro assay and screening, in vivo efficacy and safety study, antibody transient expression, stable cell line, and scale up production. These included: -- One study, to determine whether the superior activity of the modified anti-CD20 human-mouse chimeric antibody exposed unexpected adverse activity that may not have been seen with the less cytotoxic unmodified antibody. The chimeric antibody cetuximab contains a higher proportion of mouse protein and thus is associated with a higher incidence of hypersensitivity reactions. |
Chimeric Antibody |
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