chimera

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chimera

 [ki-me´rah]
an organism whose body contains different cell populations derived from different zygotes of the same or different species, occurring spontaneously or produced artificially.

chi·me·ra

(kī-mēr'ă, ki-),
1. In experimental embryology, the individual produced by grafting an embryonic part of one animal onto the embryo of another, either of the same or of another species.
2. An organism that has received a transplant of genetically and immunologically different tissue, such as bone marrow.
3. Dizygotic twins that exchange immunologically distinct types of erythrocytes.
4. A protein fusion in which two different proteins are linked through peptide bonds; usually genetically engineered. Chimeric antibodies may have the Fab fragment from one species fused with the Fc fragment from another.
5. Any macromolecule fusion formed by two or more macromolecules from different species or from different genes.
[L. Chimaera, G. Chimaira, mythic monster (lit. a she-goat)]

chimera

/chi·me·ra/ (ki-mir´ah)
1. an organism with different cell populations derived from different zygotes of the same or different species, occurring spontaneously or produced artificially.
2. a substance created from proteins or genes of two species, as by genetic engineering.chimer´ic

chimera

also

chimaera

(kī-mîr′ə, kĭ-)
n.
1.
a. An organism, organ, or part consisting of two or more tissues of different genetic composition, produced as a result of organ transplant, grafting, or genetic engineering.
b. A gene or protein consisting of parts from two different genes or proteins that are normally distinct, sometimes derived from two different species.
2. An individual who has received a transplant of genetically and immunologically different tissue.

chimera

[kimir′ə, kīmir′ə]
Etymology: Gk, khimaros, fire-breathing monster
an organism carrying cell populations derived from two or more different zygotes of the same or different species. Chimeras include recipients of tissue grafts from other individuals. Compare mosaic.

chimera

Any individual organism or molecule derived from 2 or more species.
 
Embryology
An organism that results when an embryonic part of one organism is grafted onto another.

Genetics
An organism with 2 or more cell lines, genotypes or karyotypes descended from at least 2 zygotes. Chimeras are very rare, only occur in twins and result from chorionic vascular anastomoses, transplantations or double fertilisations and subsequent participation of both fertilised meiotic products in one developing embryo; all hermaphrodites should be karyotyped to evaluate possible chimerism.

Molecular biology
(1) An animal formed from two different embryonic sources. In mouse genetics, targeted mutations produced in embryonic stem cells are recovered by breeding chimeric mice, resulting from the mixture of embryonic stem cells with a genetically distinct blastocyst.
(2) A clone containing genomic DNA from nonadjacent genomic segments or cDNA from two different mRNAs.

Transplantation
The term chimera was once used for a person who had received transplanted tissue—e.g., bone marrow surviving in a recipient.

chi·me·ra

(kī-mēr'ă)
1. The individual produced by grafting an embryonic part of one animal onto the embryo of another, either of the same or of another species.
2. An organism that has received a transplant of genetically and immunologically different tissue, such as bone marrow.
3. Dizygotic twins that have immunologically distinct types of erythrocytes.
4. A protein fusion in which two different proteins, usually from different species, are linked through peptide bonds; usually genetically engineered. Chimeric antibodies may have the Fab fragment from one species fused with the Fc fragment from another.
5. Any macromolecule fusion formed by two or more macromolecules from different species or from different genes.
[L. Chimaera, G. Chimaira, mythic monster (lit. a she-goat)]

chimera

An organism that contains a mixture of genetically different cells derived from more than one ZYGOTE. A chimera may, for instance, occur as a result of fertilization by more than one spermatozoon; fusion of two zygotes; an ALLOGENEIC bone marrow graft; cell exchange between dizygotic twin fetuses; or combination of portions of embryos of different species. Compare MOSAICISM. The term derives from the name of a mythical monster with a lion's head, a goat's body, and a serpent's tail.

chimera, chimaera

1. a mythological, fire-spouting monster with a lion's head, goat's body and serpent's tail.
2. an animal whose body contains different cell populations derived from different zygotes of the same or different species, occurring spontaneously or produced artificially; i.e. an individual composed of a mixture of genetically different cells.

chimera protein
see fusion protein.
References in periodicals archive ?
The chimaera weighed between two and five kilograms, but was already dead when it was pulled from the net.
Sharks, rays and chimaeras tend to grow slowly and produce few young, which leaves them particularly vulnerable to overfishing," said Sonja Fordham, IUCN SSG Deputy Chair and president of the Washington, DC-based Shark Advocates International, a project of The Ocean Foundation.
In fact, only 23 percent of shark, ray and chimaera species are categorized as being safe, or of "least concern," IUCN officials said.
As a children's book, it inculcates bourgeois values in the young; using the universal trappings of classical mythology; in one reading of "The Chimaera," for instance, the myth's narrator, college student Eustace Bright, offers his cousin Primrose a story "aimed at taming or domesticating nascent female desire through an ideology of love" (Ginsberg 263).
a professor at New York Medical College, announced their application for a patent on all technologies that could lead to the creation of "human/animal chimaeras," or animals that contain a mixture of human and nonhuman genetic material.
Pristis microdon belongs to the wideranging family of cartilaginous fishes called elasmobranchs (from the Greek words elasmos, meaning beaten metal and bragkhia, meaning gills) which includes sharks, rays and chimaeras or ghost sharks.
as the Poets make their Centaures, Chimaeras, or other Monsters never seen" (45.
Scientific precision and interpretations untainted by ideology, which at times in this book seems to be Howitt's goals, are total chimaeras.
The elephant sharks (Callorhinchus mili), although not a shark but a member of the branch of cartilaginous fish known as chimaeras, have hardly changed for 420 million years, genome mapping studies have showed.
Stevens JD, Bonfil R Dulvy K, Walker PA (2000) The effects of fishing on sharks, rays and chimaeras (Chondrichthyes) and die implications for marine ecosystems.
The elephant shark and its cousins the sharks, rays, skates and chimaeras are the world's oldest-living jawed vertebrates.
Fish specimens were measured to the nearest mm following the methods of Compagno (1984) for selachians, De Buen (1959) for batoids and Hardy and Stehmann (1990) for chimaeras.