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chenodeoxycholic acid |
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chenodeoxycholic acid /che·no·de·oxy·cho·lic ac·id/ (ke?no-de-ok?se-kol´ik) a primary bile acid, usually conjugated with glycine or taurine; it facilitates fat absorption and cholesterol excretion. chenodeoxycholic acid a primary bile acid, C24H40O4, administered as an anticholelithogenic agent. Called also chenodiol. |
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Short of surgery, the only gallstone therapy currently approved in the United States is treatment with chenodeoxycholic acid. Oral administration of UDCA in humans leads to a significant change in the relative proportions of the biliary and serum bile acids, such that UDCA becomes the major bile constituent (about 50 percent when a 13-15 mg/kg/day dose is given) and naturally replaces cholic and chenodeoxycholic acids. |
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chenodeoxycholic acid
