Any of several compounds that inhibit the functioning of a particular cellular glycoprotein and make cells, especially tumor cells, sensitive to chemotherapeutic agents.
References in periodicals archive ?
Effects and mechanisms of proton pump inhibitors as a novel chemosensitizer on human gastric adenocarcinoma (SGC7901) cells.
Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs.
For instance, the combination of acetamide derivatives N(2-hydroxyphenyl) acetamide (NA-2) and Temozolomide (TMZ) synergistically induces apoptosis of human glioblastoma U87 cells [22], suggesting that acetamide derivatives could be a chemosensitizer for enhancing other chemotherapy agent-induced anticancer effects.
Antisense and non-antisense effects of antisense Bcl-2 on multiple roles of Bcl-2 as a chemosensitizer in cancer therapy.
22 February 2011 - France-based pharmaceutical company AB Science SA (EPA: AB) announced yesterday publication in The Veterinary Journal of results from a preclinical study showing that masitinib has potential as a chemosensitizer.
CHQ also has potential for use as a chemosensitizer in cancer in conjunction with some conventional antineoplastic agents.
In preclinical studies, OGX-427 has shown to significantly reduce levels of Hsp27, induce apoptosis in several cancer cell lines, has single agent anti-tumour activity, and acts as a chemosensitizer with several cytotoxic drugs, including docetaxel.
Synthetic lethal screen identification of chemosensitizer loci in cancer cells.
CAST (Chemotherapy Active Support Technology) is a multivalent all-natural vegetarian formula acting as a chemosensitizer and an inhibitor of matrix metalloproteinases (MMPs) as well.
AB Science is developing masitinib in veterinary medicine in oncology, including several studies to further investigate masitinib's potential as a chemosensitizer, as well as in non oncology diseases, such as canine atopic dermatitis or asthma in cats.
To answer this question we proposed to determine the intrinsic adherence (ira values) for nematocysts discharged from Type B and from Type C CSCCs as a function of chemosensitizer concentration.
In vivo evidence of gamma-tocotrienol as a chemosensitizer in the treatment of hormone-refractory prostate cancer.