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chemosensitizer |
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| This subversion of the MXR defense by multiple substrates or inhibitors of efflux transporters is referred to as chemosensitization, and compounds that cause this behavior are referred to as chemosensitizers (Epel 1998; Kurelec 1997; Smital and Kurelec 1998b). The Company anticipates the initiation of Phase II clinical trials in LE-AON later this year for various indications, as both a radiation sensitizer as well as a chemosensitizer. Chemosensitizers are now being tested in clinical trials to prevent tumor cells from resisting harsh chemotherapeutics. |
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