chemosensitize

chemosensitize

(kē-mō-sen'si-tīz),
To alter susceptibility of a target cell or organism, such that a therapeutic agent, having become ineffective, becomes effective again; observed with antineoplastic and antiparasitic drugs.
References in periodicals archive ?
Resveratrol's ability to chemosensitize cancers to therapy has been attributed to the regulation of many signaling molecules including drug transporters, cell survival and cell proliferation regulators, and members of the nuclear factor kappa B and signal transducer and activator of transcription 3 signaling pathways (5).
studied the controlled release of etanidazole, a compound that is cytotoxic to tumor cells and can chemosensitize some alkylating agents by activating their tumor cell killing capabilities, encapsulated in sprayed dried poly(DL-lactide-co-glycolide) (PLGA) microspheres and compressed into implantable discs.
We proposed a so-called nematocyst release response controlled by soluble, prey-derived chemicals also known to both chemosensitize nematocyst discharge and initiate the feeding response.
Conclusion: In brief, our results suggested that resveratrol chemosensitizes doxorubicin in combination, through inhibiting breast cancer cells proliferation and invasion, and inducing apoptosis via suppression of chronic inflammation and autophagy.
An anti-CD19 antibody inhibits the interaction between P-gp and CD19, causes P-gp to translocate out of lipid rafts and chemosensitizes a MDR lymphoma cell line.
The data were presented in an abstract titled "Systemic and Local Delivery of E1A-Cationic Lipid Complex Chemosensitizes Breast and Ovarian Cancer Cells In Vivo.