chemosensitize

chemosensitize

(kē-mō-sen'si-tīz),
To alter susceptibility of a target cell or organism, such that a therapeutic agent, having become ineffective, becomes effective again; observed with antineoplastic and antiparasitic drugs.
References in periodicals archive ?
Use of genes to chemosensitize HIV-1 infected cells 145
studied the controlled release of etanidazole, a compound that is cytotoxic to tumor cells and can chemosensitize some alkylating agents by activating their tumor cell killing capabilities, encapsulated in sprayed dried poly(DL-lactide-co-glycolide) (PLGA) microspheres and compressed into implantable discs.
An anti-CD19 antibody inhibits the interaction between P-gp and CD19, causes P-gp to translocate out of lipid rafts and chemosensitizes a MDR lymphoma cell line.
The data were presented in an abstract titled "Systemic and Local Delivery of E1A-Cationic Lipid Complex Chemosensitizes Breast and Ovarian Cancer Cells In Vivo.
Escin, a pentacyclic triterpene, chemosensitizes human tumor cells through inhibition of nuclear factor-kappaB signaling pathway.