Flavonoid dimers as bivalent modulators for P-glycoprotein-based multidrug resistance, synthetic apigenin homodimers linked with defined-length polyethylene glycol) spacers increase drug retention and enhance chemosensitivity
in resistant cancer cells.
Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity
Preclinical presentations include a late breaking abstract on the impact of MM-121, an ErbB3-targeting antibody, on chemosensitivity
in heregulin-stimulated tumor cell models, a poster on the mechanism of MM-131, a novel bispecific antibody targeting the c-Met pathway, and a poster on the effect of MM-302 on breast cancer tumor models with intermediate levels of HER2.
The tests were supposed to be chemosensitivity
tests, to guide therapy in patients with breast cancer and lung cancer.
High-dose parenteral ascorbate enhanced chemosensitivity
of ovarian cancer and reduced toxicity of chemotherapy.
The triple negative paradox: primary tumor chemosensitivity
of breast cancer subtypes.
They appear to have the same initial chemosensitivity
, early recurrence and poor prognosis as renal MRT and AT/RT.
Co-administration of piperine with MTX inhibiting the P-glycoprotein and cytochrome p-450 enzymes enhances the efficacy of drug, makes drug more effective against cancer and transporter inhibitors (curcumin) increases the intracellular drug accumulation and restores the chemosensitivity
and perception of dyspnea in patients with a history of near-fatal asthma.
Inhibition of the JAK-STAT3 signaling pathway by Ganoderic acid A enhances chemosensitivity
of HepG2 Cells to cisplatin.
from cell lines: forensic bioinformatics and reproducible research in high-throughput biology.
Perhaps they could be used more broadly for chemosensitivity
, as we demonstrated in the NEJM study, for regenerative medicine to replace organ tissue that is damaged, for diabetes -- we could remove remaining islet ells in the pancreas, expand them, and implant them back into the pancreas -- and to treat the many storage diseases caused by lack of liver enzymes.