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Chemokine receptor

   Also found in: Wikipedia 0.01 sec.
Chemokine receptor
A receptor on the surface of some types of immune cells that helps to mediate entry of HIV into the cell.
Mentioned in: AIDS


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Gunn's team studied several different types of mice that were missing other chemokines or chemokine receptors, and found that the animals lacking the Ccr2 chemokine receptor-which controls the migration of inflammatory monocytes-had much lower accumulation of monocyte-derived dendritic cells and TH1 responses.
Topics of the research and review papers include Nijmegen Breakage Syndrome, models of genetic and physiological heterogeneity, polymorphisms in CCR5 chemokine receptor genes, genetic anticipation, inheritance in mammal litter sizes in different populations, heritable and molecular genetic variation in mate choice and mating-related genes, osteogenesis imperfecta, tuberous sclerosis complex, and findings in Danon disease, a rare X-linked dominant disorder.
San Diego, CA) has patented transmembrane receptors, particularly to a human G protein-coupled receptor, more particularly to a CXC chemokine receptor subtype 3 (CXCR3), and most particularly to mutated (non-endogenous) version of the human CXCR3 for evidence of constitutive activity and uses thereof.
 
 
 
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