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chemokine |
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chemokine /che·mo·kine/ (ke´mo-kīn) any of a group of low molecular weight cytokines identified on the basis of their ability to induce chemotaxis or chemokinesis in leukocytes (or in particular populations of leukocytes) in inflammation.
chemokine [kē′mōkīn] Etymology: Gk, chemeia, alchemy + kinēsis, movement any of a group of low-molecular-weight cytokines, such as interleukin-8, identified on the basis of their ability to induce chemotaxis or chemokinesis in leukocytes (or in particular populations of leukocytes) in inflammation. The group is divided into four subgroups on the basis of genetic, structural, and functional criteria. They function as regulators of the immune system and may also play roles in the circulatory and central nervous systems. See also cytokine. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Thus, the cytokine profile demonstrates that the levels of Th1 chemokine CXCL10 was highly elevated and that the levels of chemokines IL-8/CXCL8, CCL2, and CXCL9 were moderately elevated. By administering an effective dose of a specific neutralizing agent for chemokine CXCL10, and thus promoting the histological and functional repair of hepatic cells, we hope to offer a treatment that will improve the quality of life of patients who suffer from acute liver failure. The mutation that has been implicated in West Nile disease susceptibility shuts down the production of a protein called chemokine receptor-5 (CCR5). |
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