chemically-modified hemoglobin

chemically-modified hemoglobin

Transfusion medicine A stabilized Hb solution designed to carry O2 or serve as a blood substitute; CMHs remain in the intravascular space for 12 hrs to 4 days and may interfere with measurement of Hb, BR, and lipids, but do not interfere with antibody testing. See Blood substitute, Perfluorocarbon.
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Chemically-modified hemoglobin can cause interference in HbA1c methods such as ion exchange and electrophoresis which separate hemoglobin species on the basis of charge differences.
It is free from interference from chemically-modified hemoglobin.

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