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chemical mediator

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chemical mediator,
a neurotransmitter chemical, such as acetylcholine.


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If surrounding T and B white blood cells have been sensitized to this particular allergen, the mast and basophil cells will release histamine and other inflammatory chemical mediators (cytokines, interleukins, leukotrienes, and prostaglandins) into the surrounding tissue, causing several systemic effects, such as vasodilation, mucous secretion, nerve stimulation and smooth muscle contraction.
If surrounding T and B white blood cells have been sensitized to this particular allergen, the mast and basophil cells will release histamine and other inflammatory chemical mediators (cytokines, interleukins, leukotrienes, and prostaglandins) into the surrounding tissue, causing several systemic effects, such as vasodilation, mucous secretion, nerve stimulation and smooth muscle contraction.
Pretreatment with inhaled cromolyn sodium results in inhibition of mast cell degranulation, thereby blocking release of the chemical mediators of inflammation.
 
 
 
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