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carcinogenesis |
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carcinogenesis [kär′sinəjen′əsis] the process of initiating and promoting cancer. Compare malignant transformation, oncogenesis, sarcomagenesis, tumorigenesis. carcinogenesis [kahr″sĭ-no-jen´ĕ-sis] production of cancer. ![]() Multistep model of carcinogenesis. The stepwise genetic alterations that lead to colorectal cancer. From Aspinall and Taylor-Robinson, 2001. carcinogenesis production of cancer. biological carcinogenesis viruses and some parasites are capable of initiating neoplasia. See viral oncogenesis, Spirocercalupi. chemical carcinogenesis numerous chemicals have been identified as carcinogenic. physical carcinogenesis
includes ultraviolet radiation, ionizing radiation and asbestos. carcinogenesis Transformation, tumourigenesis Oncology A series of genotypic and phenotypic changes that result in a cell being identified as malignant by virtue of its metastatic potential. See Cancerization, Chemical carcinogenesis, Inducer, One-hit/two-hit model, Proto-oncogenes, Tumor promoter, Tumor suppressor.
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